Research on procuring data for exposure assessment

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What it's about

Standardised, simple screening methods as well as modern statistical methods are needed to collect data and assess exposure. BfRshort forGerman Federal Institute for Risk Assessment develops these methods further in order to be able to give a realistic assessment of the risks with an acceptable degree of effort.

Our tasks

The risks linked to foods and consumer products are diverse and complex. In order to identify a possible threat to consumers, information is needed about the intake of pathogens and contaminants. The precondition for risk assessment is, therefore, knowledge about the occurrence, spread and intake of harmful pathogens, contaminants, products and their chemical substances. One focus of BfRshort forGerman Federal Institute for Risk Assessment research is, therefore, the development of methods to collect data within the framework of risk analysis as the basis for exposure assessment.

Standardised, simple screening methods as well as modern statistical methods are needed to collect data and assess exposure. BfRshort forGerman Federal Institute for Risk Assessment develops these methods further in order to be able to give a realistic assessment of the risks with an acceptable degree of effort.

The focus of research is the development of refined variability-related approaches to exposure estimation and the collection of high-quality data for exposure estimation in the area of food safety. Important data sources are food consumption studies, levels of agents in food and consumer products, transfer studies in farm animals on the transition of undesirable substances from feed to food of animal origin, as well as data that provide information about the handling of consumer products in daily life (consumer behaviour).

Research projects

  • Exposure assessment for chemicals and product safety

  • Exposure assessment for textiles, toys and non-textile care items

    BfR carries out research in the field of exposure through textiles, toys and non-textile care articles.

  • Model parameters for prospective intake estimates

    The BfR is involved in the safety assessment of novel foods and food ingredients and develops models to estimate exposure to the ingredients they contain.

  • Probabilistic exposure assessment

    Exposure assessment can help to determine the type, nature, frequency and intensity of contacts between the population and the contaminant that is to be assessed. There are various approaches for estimating exposure.

  • KiESEL - The Children's Nutrition Survey to Record Food Consumption

    The KiESEL study recorded the food consumption of infants, toddlers and children from the age of six months up to and including five years.

  • The COPLANT Study - Research on Plant-Based Nutrition

Third party projects (selection)

Research projects

Science News on exposure assessment – The BfRshort forGerman Federal Institute for Risk Assessment in Journals

Datum Titel Fachzeitschrift
External Link: Hazard characterization of the mycotoxins enniatins and beauvericin to identify data gaps and improve risk assessment for human health Archives of Toxicology
External Link: Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to 2- and 3-monochloropropanediol (urinary excretion) and glycidol (hemoglobin adduct N-2,3-dihydroxypropyl-Val) Archives of Toxicology
External Link: Mono-n-hexyl phthalate: exposure estimation and assessment of health risks based on levels found in human urine samples Archives of Toxicology
External Link: Quantification of sixteen cannabinoids in hemp seed edible oils and the influence of thermal processing on cannabinoid contents and profiles Food Additives & Contaminants
External Link: Prenatal and Early Postnatal Exposure to Persistent Organic Pollutants (POPs): What Is the Correlation between Dioxins and Long-Chain Per- and Polyfluorinated Alkyl Substances (PFAS)? Environ Health Perspect
External Link: Proportionality principle revisited-relationship between application ratesand pesticide residue concentrationsin food commodities Pest Management Science
External Link: Summary and derived Risk Assessment of 3D printing emission studies Atmospheric Environment
External Link: Comment on “Maternal Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Male Reproductive Function in Young Adulthood: Combined Exposure to Seven PFAS” Environmental Health Perspectives
External Link: Roadmap for Mixture Toxicity published EFSA Journal
External Link: 3-MCPD as contaminant in processed foods: State of knowledge and remaining challenges Food Chemistry
External Link: Transdermal absorption of 13C4-perfluorooctanoic acid (13C4-PFOA) from a sunscreen in a male volunteer - What could be the contribution of cosmetics to the internal exposure of perfluoroalkyl substances (PFAS)? Environment International
External Link: Results of the BfR MEAL Study: In Germany, mercury is mostly contained in fish and seafood while cadmium, lead, and nickel are present in a broad spectrum of foods Food Chemistry: X
External Link: Fluoridanwendungen bei Kindern und Jugendlichen in Deutschland Oralprophylaxe & Kinderzahnheilkunde
External Link: Alkenylbenzenes in Foods: Aspects Impeding the Evaluation of Adverse Health Effects Foods
External Link: Internal exposure to perfluoroalkyl substances (PFAS) in vegans and omnivores International Journal of Hygiene and Environmental Health
External Link: A prospective whole-mixture approach to assess risk of the food and chemical exposome Nature Food
External Link: Bioactivation of estragole and anethole leads to common adducts in DNA and hemoglobin Food and Chemical Toxicology
External Link: A scientific review of colorful textiles Journal of Consumer Protection and Food Safety
External Link: Internal exposure to perfluoroalkyl substances (PFASs) and biological markers in 101 healthy 1-year-old children: associations between levels of perfluorooctanoic acid (PFOA) and vaccine response Archives of Toxicology
External Link: Aggregated aluminium exposure: risk assessment for the general population Archives of Toxicology
External Link: Vergleich von drei Emissionsprüfkammern für die Untersuchung von Verbraucherprodukten Indoor Air - International Journal of Indoor Environment and Health
External Link: Consumer protection and risk assessment: sensitising substances in consumer products Allergo Journal International
External Link: Refinement of dietary exposure assessment using origin-related scenarios Journal of Exposure Science & Environmental Epidemiology
External Link: Comparison of lead levels in edible parts of red deer hunted with lead or non-lead ammunition Science of The Total Environment

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