Defined in Regulation (EC) No 1907/2006 (REACH) as the derived level of exposureExposureTo glossary to a substance ‘above which humans should not be exposed’. One or more DNELshort forDerived No Effect Level values are determined for a substance, taking into account the most likely route(s) of exposure and the most likely duration and frequency of exposure. The derivation of these values is based on toxicological studies (human or non-human). The value is usually specified in mgshort formilligram/kgshort forkilogram body weight per day.