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Integrating VEGA, toxRead, MERLIN-Expo and ERICA into a single platform for risk assessment and substitution of risky substances (LIFE VERMEER)


This third-party funded project is conducted in the framework of the BfR research programme to harmonise and standardise assessments of exposure.

EU grant number: LIFE16 ENV/IT/000167

Project homepage: -

Project description:

LIFE VERMEER is an advanced project for the substitution of substances. Indeed it will provide a flexible, user-friendly tool of broad applicability. In the case of the substitution of a risky substance, a number of issues have to be addressed to ensure  that the candidate compound does not present another critical issue. Thus, multiple assessments has to be done to cope with the different possible situations related to hazards towards human health or living species, or persistence or bioaccumulation of the chemical, keeping into account the different exposure scenarios, again related to humans or living species. Nowadays this task has to be addressed through a series of tools, with practical and theoretical difficulties, because the different systems may not provide a complete picture. The tool we will provide, ToxEraser, will be of broad application, as demonstrated through a large series of heterogeneous case studies. Furthermore, LIFE VERMEER will provide a unique tool  for the assessment of  mixtures of substances too. This tool, SPHERA, will be functional to ToxEraser, but will be very useful per se, offering the possibility to address the risk assessment of mixtures in a simplified but powerful way.

Project partners:

  • Mario Negri Institute for Pharmacological Research, Italy (coordination)
  • Angel Consulting, Italy
  • Électricité de France SA, France
  • Facilia AB, Sweden
  • National competence centre for Industrial Safety and Environmental Protection, France
  • Kode srl, Italy
  • SC Sviluppo chimica S.p.A., Italy
  • Scientific Institute of Public Health, Belgium


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