You are here:

Brucella spp. of amphibians comprise genomically diverse motile strains competent for replication in macrophages and survival in mammalian hosts

The present work is a comprehensive molecular and phenotypic study of a large collection of isolates from African bullfrogs building on a previous preliminary description of two of these strains. The authors conducted an in-depth genome analysis and also evaluated the virulence of the potentially new Brucella species for mammalian hosts both in in vitro and in vivo models of infection.

Brucella spp. of amphibians comprise genomically diverse motile strains competent for replication in macrophages and survival in mammalian hosts
Sascha Al Dahouk1, Stephan Köhler, Alessandra Occhialini, María Pilar Jiménez de Bagüés5, Jens Andre Hammerl, Tobias Eisenberg, Gilles Vergnaud,Axel Cloeckaert, Michel S. Zygmunt, Adrian M. Whatmore, Falk Melzer, Kevin P. Drees, Jeffrey T. Foster, Alice R. Wattam & Holger C. Scholz

Nature.com, Scientific Reports 7,
Article number:44420 (2017)
Published online: 16 March 2017
DOI:10.1038/srep44420

https://www.nature.com/articles/srep44420

Up