Research on the use of QSAR in chemical assessment
What it's about
As part of the authorisation procedure for chemicals and other toxicologically relevant substances, extensive toxicological testing is required.
Background
In order to reduce the number of these animal experiments, there is a need to develop methods that predict or estimateEstimateTo glossary the inherent toxic properties of chemical substances.
One such method is quantitative structure-activity relationships (QSAR), which, based on mathematical modelling of structure-activity relationships, predicts or estimates the toxic effect of chemical substances after repeated administration.
Research areas
- Development of an optimised read-across system for predicting and estimating the toxic properties of chemical substances as a basis for their health assessment, and the use of the information and data obtained to develop and validate prediction models.