Category Research project
  • Alternativmethoden zum Tierversuch

External Validity of the Wildling Mouse Model in Health and Disease

Project status
In Progress
Project start
Jun 2022
Project end
Dec 2025
Acronym
C3R HeaD
Department
Experimentelle Toxikologie und ZEBET

Description and Objective

The wildling mouse is a new preclinical mouse model that - in contrast to conventional laboratory mice - has a natural microbiome. Results from research using animal models should ideally be generalisable and applicable to a broader context. However, the external validity of the Wildling mouse model has not yet been systematically evaluated. The overall goal of the C3R-HeaD study is to assess the external validity of research conducted with wildling mice compared to SPF mice.
Type of project

Third-party funded project

Areas of research

Alternativmethoden zum Tierversuch / Gesundheit von Mensch, Tier und Umwelt (One Health) / Moderne Methoden in der Toxikologie

Organisational units and partners

Lead unit: Verhalten von Versuchstieren und Refinement (92)
Contact persons: Prof. Dr. Lars Lewejohann, Dr. Kai Diederich, Prof. Dr. Gilbert Schönfelder
External partner: Charité - Universitätsmedizin Berlin

Funding body and grant number

Charité - Universitätsmedizin Berlin
n.a.

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