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["Introduction"]
["This calculator presents a tool to facilitate the estimation of external livestock exposure to biocidal active substances as described in the Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure (1). In addition, it allows estimation of the worst-case consumer exposure (WCCE) from the calculated external livestock exposure as explained in the EMA-CVMP Guideline on risk characterisation and assessment of maximum residue limits (MRL) for biocides (2). This calculator applies assumptions and default values as given in both guidance documents. For references and explanations on these values please refer to the respective guidance document (1, 2). "]
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["Section 6 of the Guidance on BPR (1) focusses on external exposure assessment of livestock animals. In an initial screening step it is assumed that the entire amount of biocidal product applied is taken up by animals regardless of the route of exposure. The result of the exposure estimate is compared to a pre-defined threshold of concern. If this trigger value (0.004 mg a.s./kg bw/d) is exceeded a realistic worst-case estimate (RWCE) should be performed for each relevant route of exposure (oral/dermal/inhalative) taking into account the fraction of applied product available for each route. The results for each route of exposure estimates are then added up to arrive at a total exposure value. \nIf the trigger value (0.004 mg a.s./kg bw/d) is still exceeded it should be considered whether further refinement of the RWCE is possible. Such refinements may include the use of more realistic calculation models (e.g. ConsExpo model (3) for estimation of inhalative exposure, see information on spreadsheet \"Refinement Notes Inhalation\") or the application of additional risk mitigation measures (e.g. rinsing of treated surfaces).\nIn case the realistic worst-case estimate cannot be further refined to reduce the estimated exposure level below the trigger value, the worst-case consumer exposure (WCCE) should be estimated and compared to the acceptable daily intake (ADI) and /or the acute reference dose (ARfD). The process for estimating WCCE is described in the EMA-CVMP Guideline (2). Initially it is assumed that the estimated external livestock exposure reflects the internal livestock exposure. In the absence of more substance specific data, empirical transfer factors (based on the log PO/W) may be considered to estimate the maximum transfer of an external oral dose to livestock edible tissues (4). "]
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["Both, screening and realistic worst-case estimates, are based on information on the intended use and on a set of default values. Please note that the use of this calculator requires expert judgement with regard to choice of scenario, application of assumptions and default values. It does not give a ready-to-use report with results but merely facilitates the execution of calculations for all animal species. "]
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["Important notice: We have taken great care with the compilation and verification of the contents of this calculator. \nHowever, we do not assume any guarantee for its results, completeness or that it is kept up to date.  Also, we do not assume any  responsibility for any external contents referenced to.\n\n© German Federal Institute for Risk Assessment, 2021"]
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["How to use this calculator"]
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["For Screening Scenarios go to spreadsheet \"Report (Screening)\"\n1. Choose screening scenario\n2. Enter maximal application rate (apply the appropriate units!)\n3. Click \"Generate Report\""]
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["For Realistic Worst-Case Scenarios go to spreadsheet \"Report (Realistic worst case)\"\n1. Choose all scenarios that apply\n2. Enter all required information in the boxes that are highlighted (maximal application rate and/or other substance specific information)\n3. If appropriate a refinement factor may be introduced\n4. Click \"Generate report\""]
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["For Worst-Case Consumer Exposure go to spreadsheet \"Report (WCCE)\"\n1. The WCCE will automatically be calculated based on the entries made in the spreadsheet \"Report (Realistic worst case)\". The model will automatically take the animal species with the highest total exposure (animal species written beneath the calculated WCCE value for edible tissue, milk and eggs). \n2. If available enter the acceptable daily intake (ADI) and acute reference dose (ARfD) and the percentage of the ADI/ARfD for each WCCE model will be given.\n3. (optional) Enter log PO/W for use of empirical transfer factors"]
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["Please see also description of scenarios below."]
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["Interpretation of results"]
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["The choice of the adequate scenario for calculation of livestock exposure depends on the intended use, e.g. type of product formulation/application, presence/absence of animals during treatment etc. The results should be checked for plausibility with regard to the relevant route of exposure, the fraction of applied product available for each route, the choice of relevant animal, the refinement parameters applied etc."]
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["The calculator gives results for all animal species for which default values for the chosen scenario are available in the guidance document (1). Not all scenarios apply to all animal species. Interpretation of results should focus on the animal species relevant for the specific assessment. Please note that the choice of relevant animal species depends on the specific conditions that apply for the intended use of the biocidal product. Generally representative livestock species include calves, beef and dairy cattle, pigs, broiler chicken and laying hens. It may also be possible that additional livestock may be identified as representing the worst case. "]
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["In the results table values above the trigger value are highlighted in red. If the trigger value is exceeded in the realistic worst-case estimate a refined external exposure estimate according to the principles for assessment Step 2 as explained in the guidance document (1) may be performed. \nAlternatively an approach that proceeds beyond external livestock exposure estimation may be applied as described in the EMA Guideline on Risk Characterisation and Assessment of Maximum Residue Limits (MRL) for Biocides (2) starting with an estimation of  the WCCE. In the spreadseet \"Report (WCCE)\" the result of WCCE calculation based on the results of the RWCE is given. \n"]
["Please note that the trigger value approach is not applicable for substances with a potential for accumulation, for particularly toxic substances for which even small residues can lead to an exceedance of ADI, and for substances with non-threshold effects."]
["For calculation of the total exposure estimate please consider that some scenarios for chicken and pigs distinguish between several housing conditions. "]
["NB: Results for the examples given in the guidance document (1) may deviate from results produced by this calculator due to rounding differences."]
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["Scenarios: Model Description, Assumptions, Maximal application rate, Default Values"]
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["The exposure models presented in this calculator are not a comprehensive collection of scenarios. During evaluation it must be ensured that the chosen scenario is applicable to the intended use to be evaluated. Adjustment of existing scenarios or development of new scenarios will be required on a case-by-case basis. The list of scenarios in this calculator may be extended as more active substances and their uses in biocidal products are evaluated. "]
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["One simple option for refinement of the scenarios is to apply a (sufficiently justified!) refinement factor for the realistic worst case scenarios (e.g. emission factors for spray treatment (Default Table 4), account for animal activity for alveolar ventilation rate, targeted spot treatment etc). "]
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["Most scenarios only require the input of the maximal application rate of the active substance. Please note that the proper units must be used. Details on the required input data for the individual scenarios are given in the scenario descriptions below. \nTime intervals between applications are not considered in the models applied, instead the worst case is considered which assumes the presence of the highest possible amount of residue, which is the residue present on the day of application. \nFor spray treatments an emission factor may be applicable that accounts for the fraction of biocidal product emitted to the treated surface/floor. (NB Check if emission factors for spray treatment are already included in the model or not!)"]
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["The following list gives a short description together with input requirements for the scenarios applied in this calculator: "]
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["Screening scenarios"]
["Surface Treatment of animal housing (floor&wall of stable without partitions) \n(see Examples 1.1/1.2, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: \nComplete wall and floor areas  of animal housing (without partitions) are treated with the biocidal product.\nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: wall+floor area per stable (m2) (Default Table 2), No. of animals per stable (Default Table 2), body weight (kg) (Default Table 1)"]
["Surface Treatment of animal housing (individual animal surrounded by 3 or 4 walls)\nDescription/Assumptions: All surfaces of the animal housing are treated with the biocidal product. This model considers the maximum wall and floor area within reach of the animal, taking into account that the individual animal is surrounded by 3-4 walls (see Default Table 2)\nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: maximal area (wall+floor) within reach of animal (m2) (Default Table 2), body weight (kg) (Default Table 1)"]
["Surface treatment of animal housing (floor only)\nDescription/Assumptions:\nFloor area of animal housing is treated with the biocidal product. \nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: floor area per stable (m2) (Default Table 2), No. of animals per stable (Default Table 2), body weight (kg) (Default Table 1)"]
["Surface treatment of animal housing (wall only)\nDescription/Assumptions:\nWall area of animal housing is treated with the biocidal product. \nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: wall area per stable (m2) (DefaultTable 2), No. of animals per stable (Default Table 2), body weight (kg) (DefaultTable 1)"]
["Space treatment of animal housing \n(see Example 1.3, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: The complete volume of the animal housing is treated with the biocidal product, e.g. by fogging, nebulising application etc.. Biocide residues are assumed to be distributed evenly throughout the airspace. No room ventilation is considered.\nInput Parameters: Application rate (mg/m3)\nDefault Values: animal housing volume per stable (m3) (Default Table 2), No. of animals per stable (Default Table 2), body weight (kg) (Default Table 1)"]
["Surface treatment of transport vehicle \n(see Example 1.4, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: All surfaces within a transport vehicle are disinfected with the biocidal product. The model considers a truck of 7.0 m x 2.5 m with compartments as described in Appendix 6-1, Table 54 of the guidance document (1). \nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: available floor+wall area in transport vehicle per animal (m2) (Default Table 3), body weight (kg) (Default Table 1)"]
["Space treatment of transport vehicle\nDescription/Assumptions: The complete volume of a transport vehicle is treated with the biocidal product, e.g. by fogging, nebulising application etc. The model considers a truck of 7.0 m x 2.5 m with compartments as described in Appendix 6-1, Table 54 of the guidance document (1). \nInput Parameters: Application rate (mg/m3)\nDefault Values: available volume per animal (m3) (Default Table 3), body weight (kg) (Default Table 1)"]
["Treatment of feed\n(see Example 2.3, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions:  \nFeed is treated with the biocidal product according to label instructions. Animals exclusively consume treated feed. \nThis scenario can also be applied for biocidal products intended for treatment of packaging materials for feed.  For feed contaminated from packaging materials a calculation of the active substance per unit feed (mg/kg) must be performed on a case by case basis. As default it is assumed that 100% of the residues in the packaging material migrate into the feed. In Example 2.3 the guidance document describes the treatment of paper used for packaging feed. \nInput Parameters: Application rate (mg/kg feed)\nDefault Values: daily feed consumption per animal (kg) (Default Table 1), body weight (kg) (Default Table 1)"]
["Treatment of drinking water \n(see Example 2.1, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Drinking water is treated with the biocidal product. Animals exclusively consume treated water. \nInput Parameters: Application rate (mg/L)\nDefault Values: daily water consumption per animal (L) (Default Table 1), body weight (kg) (Default Table 1)"]
["Treatment of packaging material for feed\n(see Example 2.3 (page 353 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Packaging material for feedstuff has been treated with the biocidal product. The OECD ESD assumes that 90 % of the a.s. is lost in waste water and 10 % remains in the paper during paper production. Furthermore, it is assumed that 100 % of the active substance migrates from the material into the feed. 100 % of the animals´ daily feed consumption is from this contaminated feed. According to the EU Notes for Guidance for Food Contact Materials prepared by the European Food Safety Authority, it can be estimated that 1 kg of feed is in contact with 600 cm² of food packaging.\nInput Parameters: Application rate (mg/L), (a.s. concentration in water during paper production, Example 2.3. shows an example for a slimicide used in paper production)\nDefault Values: daily feed consumption per animal (kg) (Default Table 1), fraction of feed packaged in treated material (default=1), body weight (kg), (Default Table 1), paper mill waste water (Default Table 4), daily paper production per mill (Default Table 4), dry paper weight (Default Table 4), feed weight (Defaults 4), packaging surface in contact with 1 kg feed  (Default Table 4)"]
["Surface treatment of storage facilities for feedstuff (4 sizes)\nDescription/Assumptions:  Surfaces of a feed storage facility are treated with the biocidal product. This model is calculated for 4 different sizes of feed silos to account for the variety of available sizes of feed silos. In case of exceedance of the trigger value for only few smaller sizes, expert judgement is used to decide whether step 2 estimates are necessary. \nInput Parameters: Application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (Default Table 4)\nDefault Values: silo surface area (Default, Table 4), silo holding capacity (Default, Table 4), daily feed consumption per animal (kg) (DefaultTable 1), body weight (kg) (Default Table 1)"]
["Space treatment of storage facilities for feedstuff (4 sizes) \n(see Example 2.2, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: The whole volume of a feed storage facility is treated with the biocidal product, e.g. by fogging or nebulising. This model is calculated for 4 different sizes of feed silos to account for the variety of available sizes of feed silos. In case of exceedance of the trigger value for only few smaller sizes, expert judgement is used to decide whether step 2 estimates are necessary.\nInput Parameters: Application rate (mg/m3)\nDefault Values: silo volume (Default Table 4), silo holding capacity (Default Table 4), daily feed consumption per animal (kg) (Default Table 1), body weight (kg) (Default Table 1)"]
["Direct treatment of animals: teat dips \n(see Example 4.1, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nThis scenario is a special case of the \"Direct Exposure of an individual animal\" Scenario.\nDescription/Assumptions: Biocidal teat dip product is applied before or after each milking. The model assumes 2 milkings per day. The application rate is generally given by the applicant. In the absence of this information default values for applied volumes for various product formulations are available in the guidance document (1), Appendix 6-1, Table 55.\nFor the screening scenario two calculations have to be performed: Calculation A assumes that the fraction of the biocidal product that remains on the teat is dermally taken up by the animal (potential residues in milk and animal tissues), while Calculation B assumes that the fraction of the biocidal product that remains on the teat is directly carried over in the milk (no dermal uptake and thus no potential residues in tissues). \nIn case teats are disinfected before and after milking, the calculations A and B have to be performed twice, i.e. once for the pre-milking and once for the post-milking application of the biocidal product. Note that applied volume and concentration of active substance in biocidal product may differ for pre- and post-milking applications. \nInput Parameters: Application rate (mg/animal per milking) \nAR=VBP x fBP x Ca.s.   The application rate is calculated from the product volume on teats per milking (VBP) (default= 10 (Dipping)/20 (Spraying)/ 2,5 (Foam) mL/milking/animal, Default Table 4) multiplicated with the fraction of biocidal product remaining on teats (fBP) (default=0,5 according to OECD ESD for PT3)) and the concentration of active substance in product (ca.s.)(mg/ml). \nDefault Values: No. of milkings per day (default=2, Default Table 4), body weight (kg) (Default Table 1)"]
["Direct treatment of animals: hoof disinfection \n(see Example 4.1, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Animals are exposed to the total amount of active substance contained in the hoof bath tub located at the stable exit/entrance. \nInput Parameters: Application rate (mg /L hoof bath)\nDefault Values: volume of tub for hoof bath (default=325 L, Default Table 4), No. of animals per stable (Default Table 2), body weight (kg) (Default Table 1)"]
["Direct treatment of animals: ear tags \n(see Example 4.2, Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nThis scenario is a special case of the \"Direct Exposure of an individual animal\" Scenario.\nDescription/Assumptions: The animal is exposed to the total amount of active substance contained in 2 ear tags. \nInput Parameters: Application rate (mg/ear tag)\nDefault Values: No of ear tags per animal (DefaultTable 4), body weight (kg) (Default Table 1)"]
["Direct exposure of an individual animal\nfor teat dips, ear tags (per animal)\nDescription/Assumptions: An individual animal is exposed to a specified amount of biocidal product, e.g. neck collar, ear tags, teat dips containing an active substance etc .\nInput Parameters: Application rate (mg/animal)\nDefault Values: body weight (kg) (Default Table 1)"]
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["Realistic worst case scenarios"]
["Oral - Animals licking surfaces \n(see Examples 1.1/1.4 (page 343 ff.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Animals are licking surfaces that were treated with the biocidal product. \nInput Parameters: application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)\nDefault Values: tongue surface area (Default Table 4), No of licks per day (Default Table 4), body weight (kg) (Default Table 1)"]
["Oral - Uptake of feed (treatment of surfaces surrounding trough)\n(see Examples 1.1/1.2/1.3 (page 343 ff.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Troughs were not covered during biocidal spray treatment of surrounding animal housing walls, so that trough surfaces may be contaminated with the biocidal product. The model assumes that all residues contaminating the trough migrate into next feed batch which is consumed completely by the animal. \nInput Parameters: application rate (mg/m2)\nDefault Values: emission factor for spray application: fraction emitted to floor during surface treatment (default = 0,11 Default Table 4), exposed feed surface (DefaultTable 2), body weight (kg) (Default Table 1)"]
["Oral - Uptake of feed (direct treatment of trough)\nDescription/Assumptions: Inner trough surfaces were treated with the biocidal product.  The model assumes that all residues on bottom and sides of trough migrate into next feed batch which is consumed completely by the animal. \nInput Parameters: application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)\nDefault Values: exposed feed surface (Default Table 2), body weight (kg) (Default Table 1)"]
["Oral - Uptake of feed contaminated  via packaging material \n(see Example 2.3 (page 353 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Packaging material for feedstuff has been treated with the biocidal product. The OECD ESD assumes that 90 % of the a.s. is lost in waste water and 10 % remains in the paper during paper production. Furthermore, it is assumed that 100 % of the active substance migrates from the material into the feed. 10 % of the animals´ daily feed consumption is from this contaminated feed. According to the EU Notes for Guidance for Food Contact Materials prepared by the European Food Safety Authority, it can be estimated that 1 kg of feed is in contact with 600 cm² of food packaging.\nInput Parameters: application rate (mg/L), (a.s. concentration in water during paper production, Example 2.3. shows an example for a slimicide used in paper production)\nDefault Values: daily feed consumption per animal (kg) (Default Table 1), fraction of feed packaged in treated material (default=0.1, Default Table 4), body weight (kg), (Default Table 1), paper mill waste water (Default Table 4), daily paper production per mill (Default Table 4), dry paper weight (Default Table 4), feed weight (Defaults 4), packaging surface in contact with 1 kg feed  (Default Table 4)"]
["Oral - Chewing on wooden stall edgings \n(see Example 3.1  (page 355 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Wood treated with the biocidal product is incorporated into stall edgings, livestock animals are exposed orally by chewing on the wood. Wood consumption data is only based on single publications for horse and rabbit. \nInput Parameters: application rate (mg/m3)\nDefault Values: wood consumption (Default Table 4),  wood density (Default Table 4), body weight (kg) (Default Table 1)"]
["Oral - Ingestion of dead insects (poultry only) \n(see Example 1.2 (page 345 ff.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: The biocidal product is used as insecticide against flies. Chicken seek out dead flies for consumption. Each animal consumes 10 flies per day. \nInput Parameters: application rate (mg/fly/d). The application rate may be calculated from the consumption of the biocidal product by flies.  The amount of a.s. consumed by one fly depents on the characteristics of the biocidal product (BP). If the BP does not dry quickly it can be assumed that one fly consumes 3,5 mg liquid BP with the given a.s. concentration. However, if the BP dries quickly the a.s. is more concentrated (e.g. one fly consumes 3,5 mg dried sucrose containing the  a.s., the ratio of a.s. and sucrose in the BP needs to be taken into account)(Default Table 4).\nDefault Values: fly consumption per animal (Default Table 4), body weight (kg) (Default Table 1)"]
["Dermal - Rubbing against surfaces  \n(see Examples 1.1/1.3/1.4/3.1 (page 343 ff., 355 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Animal rubs on surface treated with the biocidal product. The exposure estimate includes dermal uptake as well as oral intake from grooming\nInput Parameters: application rate (mg/m2), for spray treatments the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)\nDefault Values: animal body surface area in contact with surface (m2) (DefaultTable 1), body weight (kg) (Default Table 1)"]
["Dermal - Spray treatment \n(see Example 1.2  (page 345 ff.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1)) \nDescription/Assumptions: Wall area of poultry housing is treated with the biocidal product in the presence of animals. 50% of the floor area is covered with animals, that are exposed by spray droplets falling to the floor (fraction emitted to floor: 11% of application rate). \nInput Parameters: application rate (mg/m2)\nDefault Values: wall area per stable (m2) (Default Table 2), emission factor for spray application: fraction emitted to floor during surface treatment (default = 0,11 Default Table 4), fraction of floor area covered with hens (DefaultTable 4), No. of animals per stable (Default Table 2), body weight (kg) (Default Table 1)"]
["Dermal - Walking through a hoof disinfection bath \n(Example 4.1 (page 361 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Animals walk through shallow tubs containing a hoof bath as they enter or exit the stable/milking facility. During each pass a layer of 0,01 cm of the biocidal product is in contact with the animal´s skin/hoof. For dairy cattle 3 daily passes, for beef cattle 1 daily pass through the hoof bath are assumed. \nInput Parameters: application rate (mg/L)\nDefault Values: exposed hoof area (cm2) (Default Table 4), thickness of layer of product in contact with skin  or hoof (cm) (Default Table 4), No of hoofs per animal (Default Table 4), No of daily passes through hoof bath (Default Table 4), body weight (kg) (Default Table 1)"]
["Inhalative - Saturated Vapour Concentration Model (SVC) \n(see Examples 1.1/1.2/3.1  (page 343 ff., 355 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Resting animal is exposed to air containing the a.s. at its saturated vapour concentration (SVC). To acccount for animal activity multiply result by 3.\nInput Parameters: vapour pressure of a.s. (Pa), temperature (K), molecular weight of a.s. (g/mol)\nDefault Values: gas constant (R=8,31451 J/K*mol), alveolar ventilation rate (m3/d) (Default Table 1),  body weight (kg) (Default Table 1)"]
["Inhalative - Inhalation after air space treatment \n(Example 1.3 (page 348 f.), Guidance on the BPR, Vol III Parts B+C, Section 6 (1))\nDescription/Assumptions: Resting animal is exposed to air containing the a.s. at the specified concentration (to acccount for animal activity multiply result by 3).\nInput Parameters: air concentration at time of re-entry (mg/m3)  (e.g. calculated with ConsExpo)\nDefault Values: alveolar ventilation rate (m3/d)  (Default Table 1), body weight (kg) (Default Table 1)"]
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["References"]
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["(1) Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure\nhttps://echa.europa.eu/documents/10162/23036412/biocides_guidance_human_health_ra_iii_part_bc_en.pdf"]
["(2) Guideline on Risk Characterisation and Assessment of Maximum Residue Limits (MRL) for Biocides \n(EMA/CVMP/90250/2010)\nhttp://www.ema.europa.eu/ema/index.jsp?curl=pages/regulation/general/general_content_000512.jsp&mid=&jsenabled=true"]
["(3) ConsExpo\nhttps://www.rivm.nl/en/consexpo\n(4) Leeman et al. (2007): Transfer of chemicals from feed to animal products: The use of transfer factors in risk assessment. Food additives and contaminants; 24, 1-13, DOI: 10.1080/02652030600815512 "]
["Abbreviations"]
["a.s.                             Active Substance"]
["AR                              Application Rate"]
["BP                              Biocidal Product"]
["BPR                           Biocidal Products Regulation"]
["bw                             Body Weight"]
["MRL                           Maximum Residue Limits"]
["RF                              Refinement Factor"]
["WCCE                        Worst-Case Consumer Exposure"]

{"sheet":"Document History","index":1,"n_rows":6,"n_cols":3,"rows_kept":6,"cut":false,"hidden":false,"merged":[[0,0,0,2]]}
["BfR Calculator for estimating livestock exposure \nto active substances used in biocidal products"]
[]
["Document History"]
["Version","Comment","Date"]
["Version 1.0","First edition\n\n","20.02.2012"]
["Version 2.0","(1) Addition of spreadsheets for worst-case consumer exposure (WCCE) (\"Report (WCCE)\" and \"Calc (WCCE)\")\n(2) Addition of spreadsheet for food consumption default data (chronic and acute)(\"Defaults 5 Food Cons.\")\n(3) Addition of spreadsheet for transfer factors based on the octanol–water partition coefficient (LogPOW)(\"Defaults 6 LogP_OW\")\n(4) Addition of spreadsheet for refinement of inhalation exposure estimate for livestock animals using ConsExpo Web (\"Refinement Notes Inhalation\")\n(5) Update and correct defaults to be in line with the finalized Guidance on the Biocidal Products Regulation, Vol III Parts B+C (Version 4.0, December 2017)\n a) Correction of default values as listed in Appendix 6-1 (note mistake 0.3 cm rabbits! corrected to 30 cm)\n b) Default values for transport of rabbits extracted from reference given in finalised livestock guidance\n(6) Update Screening calculations and addition of the scenario \"Treatment of packaging material for feed\" and distinction between \"Direct treatment of livestock animals -  teat dip (dermal absorption)\" and \"Direct treatment of livestock animals -  teat dip (residues in milk)\n(7) Update RWCE calculations and additon of unit converter for temperature and vapour pressure\n\n","23.07.2021"]

{"sheet":"Report (Screening)","index":2,"n_rows":181,"n_cols":7,"rows_kept":181,"cut":false,"hidden":false,"merged":[]}
["Input"]
["Choose scenario, enter maximal application rate and press \"Generate Report\". "]
["*optional information may be given in yellow boxes"]
[]
[null,"Biocidal product*","<enter product name>"]
[null,"Product type*","<choose product type>"]
[]
[null,"Active substance*","<enter substance name>"]
[null,"Concentration of a.s. in BP*","<enter concentration>","<choose unit>"]
[null,"Intended Use*","<enter description of intended use>"]
[null,"Type of product application/\nformulation*","<choose type of application>"]
[]
[null,"Screening scenario","<choose scenario>"]
[]
[null,"Maximal application rate of a.s.\n",null,{"$f":"IF(C13=A152,B152, IF(C13=A153,B153,IF(C13=A154,B154,IF(C13=A155,B155,IF(C13=A157,B157,IF(C13=A158,B158,IF(C13=A159,B159,IF(C13=A160,B160,IF(C13=A161,B161,IF(C13=A163,B163,IF(C13=A164,B164,IF(C13=A165,B165,IF(C13=A166,B166,IF(C13=A167,B167,IF(C13=A168,B168,IF(C13=A162,B162,B172))))))))))))))))","v":"choose scenario in C13"},"For assistance on how to calculate the maximal application rate please refer to the \"Read Me\" spreadsheet. Units will be automatically inserted depending on scenario."]
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[]
[]
[]
[]
["Report for Screening Scenario"]
[]
["Estimated Livestock Exposure (mg a.s./kg bw/d)"]
["The screening step assumes that the entire amount of biocidal product applied is taken up by animals regardless of the route of exposure."]
["The default values applied in the calculations were taken from the Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure."]
["Results of exposure estimates above the trigger value of 0,004 mg/kg bw/d are highlighted in red."]
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["Product types"]
["<choose product type>"]
["PT1 - Human hygiene biocidal products"]
["PT2 - Private area and public health area disinfectants and other biocidal products"]
["PT3 - Veterinary hygiene biocidal products"]
["PT4 - Food and feed area disinfectants"]
["PT5 - Drinking water disinfectants"]
["PT6 - In-can preservatives"]
["PT7 - Film preservatives"]
["PT8 - Wood preservatives"]
["PT9 - Fibre, leather, rubber and polymerised materials preservatives"]
["PT10 - Masonry preservatives"]
["PT11 - Preservatives for liquid-cooling and processing systems"]
["PT12 - Slimicides"]
["PT13 - Metalworking-fluid preservatives"]
["PT14 - Rodenticides"]
["PT15 - Avicides"]
["PT16 - Molluscicides"]
["PT17 - Piscicides"]
["PT18 - Insecticides, acaricides and products to control other arthropods"]
["PT19 - Repellents and attractants"]
["PT20 - Preservatives for food or feedstocks"]
["PT21 - Antifouling products"]
["PT22 - Embalming and taxidermist fluids"]
["PT23 - Control of other vertebrates"]
[]
[]
["Type of product application"]
["<choose type of application>"]
["spray"]
["fogging"]
["nebulising"]
["fumigation"]
["vaporizer"]
["brush application"]
["granule application"]
["dusting powder"]
["bait station"]
["other"]
[]
[]
["Units"]
["<choose unit>"]
["mg/m2"]
["mg/m3"]
["mg/kg feed"]
["mg/L water"]
["mg/L biocidal product"]
["mg/animal"]
["mg/fly/d"]
[]
[]
["Scenarios","Units for application rate"]
["<choose scenario>","choose scenario in C13",null,null,"ExplanationApplicationRate"]
["Surface Treatment of animal housing (floor&wall of stable without partitions)","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Surface Treatment of animal housing (individual animal surrounded by 3/4 walls)","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Surface treatment of animal housing (floor only)","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Surface treatment of animal housing (wall only)","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Space treatment of animal housing","mg/m³",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s.","Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for a room volume of 5 m³. AR_a.s. = (2 g / 3 L) * (1 L / 5m³) = 0,133 g a.s./m³ = 133,3 mg a.s./m³","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for a room volume of 5 m³. AR_a.s. =  5 g a.s./L * (1 L / 5m³) = 1000 mg a.s./m³"]
["Surface treatment of transport vehicle","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Space treatment of transport vehicle","mg/m³",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s.","Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for a room volume of 5 m³. AR_a.s. = (2 g / 3 L) * (1 L / 5m³) = 0,133 g a.s./m³ = 133,3 mg a.s./m³","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for a room volume of 5 m³. AR_a.s. =  5 g a.s./L * (1 L / 5m³) = 1000 mg a.s./m³"]
["Treatment of feed","mg/kg"]
["Treatment of drinking water","mg/L",null,null,"If the biocidal product (BP) needs to be diluted (e.g. concentrate) calculate the in-use concentration of a.s. ","Example \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20). AR_a.s.= 10 ml a.s./L = 5000 mg a.s./L. "]
["Treatment of packaging material for feed","mg/L",null,null,"Active substance concentration in water during paper production (mg/L = g/m³) (see Example 2.3. in guidance document on biocidal products regulation, Vol III parts B+C, section 6). If the biocidal product (BP) needs to be diluted (e.g. concentrate) calculate the in-use concentration of a.s. ","Example \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20). AR_a.s.= 10 ml a.s./L = 5000 mg a.s./L. "]
["Surface treatment of storage facilities for feedstuff (4 sizes)","mg/m²",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s."," Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. = (2 g / 3 L) * (1 L / 5m²) = 0,133 g a.s./m² = 133,3 mg a.s./m²","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for an area of 5 m². AR_a.s. =  5 g a.s./L * (1 L / 5 m²) = 1000 mg a.s./m²"]
["Space treatment of storage facilities for feedstuff (4 sizes)","mg/m³",null,null,"If the biocidal product (BP) needs to be dissolved (e.g. granules) or diluted (e.g. concentrate) calculate the in-use concentration of a.s.","Example 1 \"Granules\": 1 g undiluted BP granules contain 200 mg a.s.;10 g BP (= 2 g a.s.) are diluted with 3 L water. 1 L of diluted BP is sufficient for a volume of 5 m³. AR_a.s. = (2 g / 3 L) * (1 L / 5m³) = 0,133 g a.s./m³ = 133,3 mg a.s./m³","Example 2 \"Concentrate\": 1 ml BP concentrate contains 0,2 ml a.s.; density of the BP is 500 kg/m³ (500 mg/ml); therefore, 1 ml BP = 500 mg BP (100 mg a.s.); 50 ml BP concentrate are diluted in 1 L water (1:20, concentartion_a.s= 10 ml a.s./L = 5 g a.s./L). 1 L of diluted BP is sufficient for a volume of 5 m³. AR_a.s. =  5 g a.s./L * (1 L / 5m³) = 1000 mg a.s./m³"]
["Direct treatment of animals: teat dips","mg/animal/milking",null,null,"AR=V_BP * f_BP * C_a.s. The application rate is calculated from the product volume on teats per milking (V_BP default= 10 (for spraying use 20 and for foaming use 2,5) mL/milking/animal) multiplicated with the fraction of biocidal product remaining on teats (f_BP default=0,5 according to OECD ESD for PT3)) and the concentration of active substance in product (mg/ml).  "]
["Direct treatment of animals: hoof disinfection","mg/L hoof bath"]
["Direct treatment of animals: ear tags","mg/ear tag "]
["Direct exposure of an individual animal","mg/animal"]
[]
[]
[]
[]
[]
[]
["Concentration of a.s. in biocidal product"]
["<choose unit>"]
["mg/kg"]
["mg/L"]
["% (w/w)"]
["% (v/v)"]
["mg/unit (ear tag, bait station etc)"]

{"sheet":"Report (Realistic worst case)","index":3,"n_rows":189,"n_cols":7,"rows_kept":189,"cut":false,"hidden":false,"merged":[[29,1,29,2]]}
["Input"]
["Choose scenario(s), enter required information in the highlighted boxes and press \"Generate Report\". "]
["*Optional information may be given in yellow boxes"]
["** For refinement of the exposure model a factor may be applied on a case-by-case basis"]
[]
[null,"Biocidal product*","<enter product name>"]
[null,"Product type*","<choose product type>"]
[]
[null,"Active substance*","<enter substance name>"]
[null,"Concentration of a.s. in BP*","<enter concentration>","<choose unit>"]
[null,"Intended Use*","<enter description of intended use>"]
[null,"Type of product application/\nformulation*","<choose type of application>"]
[]
[null,"Realistic worst-case scenarios ","Max application rate of a.s.\nFor assistance on how to calculate the maximal application rate please refer to the \"Read Me\" spreadsheet.","Unit","Refinement factor**\n(default=1)","Remarks** \n(e.g. explanation for refinement factor)","The \"Read me\" spreadsheet provides assistance with scenarios, calculation of the maximal application rate and refinement factor."]
[null,null,null,"mg/m2",1,null,"Note: For spray treatment the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)."]
[null,null,null,"mg/m2",1,null,"Note: No additional refinement with emission factor of 0.11 applicable as this factor is already included in the calculation."]
[null,null,null,"mg/m2",1,null,"Note: For spray treatment the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)."]
[null,null,null,"mg/kg",1]
[null,null,null,"mg/m3",1]
[null,null,null,"mg/fly/d",1]
[null,null,null,"mg/m2",1,null,"Note: For spray treatment the application rate may be refined using an emission factor for spray application if appropriate (default=0,85 Default Table 4)."]
[null,null,null,"mg/m2",1]
[null,null,null,"mg/L",1]
[null,null,null,"mg/m3",1,null,"Note: see tab \"Refinement Notes Inhalation\""]
[]
[null,null,"Molecular weight of a.s. \n(g/mol)","Vapour pressure of a.s. \n(Pa)","Temperature \n(K)","Refinement factor**\n(default=1)","Remarks** "]
[null,null,null,null,{"$f":"C34","v":293.14999999999998},1]
[]
[]
[null,"Unit Converter",null,null,null,"Unit"]
[null,"Qty   ",20,null,null,"K"]
[null,"From   ","C",null,null,"F"]
[null,"To   ","K",null,null,"C"]
[null,"Converted Qty   ",{"$f":"CONVERT(C31,C32,C33)","v":293.14999999999998},null,null,"Pa"]
[null,null,null,null,null,"atm"]
[null,null,null,null,null,"psi"]
[null,null,null,null,null,"Torr"]
[null,null,null,null,null,"<choose unit>"]
[]
[]
[]
[]
[]
["Report for Realistic Worst-case Scenarios"]
[]
["Estimated Livestock Exposure (mg a.s./kg bw/d)"]
["The realistic worst-case step calculates exposure estimates for the different routes of exposure (inhalation, oral uptake and dermal uptake) applying route-specific parameters."]
["The results of the individual estimates are then added up to get the total external exposure value (see below Row 86)."]
["The default values applied in the calculations were taken from the Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure."]
["Results of exposure estimates above the trigger value of 0,004 mg/kg bw/d are highlighted in red."]
["Refinement factors may be applied to reduce exposure estimates in a refined realistic worst-case estimate (Tier II)."]
[]
["Animal Species"]
["Beef cattle"," - "]
["Dairy cattle"," - "]
["Calf"," - "]
["Fattening pig"," - "]
["Breeding pig"," - "]
["Breeding pig","individual housing"]
["Breeding pig","group housing"]
["Sheep"," - "]
["Lamb"," - "]
["Slaughter goat"," - "]
["Lactating goat"," - "]
["Broilers"," - "]
["Broilers","free range, litter floor"]
["Broilers","parent broilers, free range (grating floor)"]
["Broilers","parent broilers in rearing, free range (grating floor)"]
["Laying hen"," - "]
["Laying hen","battery"]
["Laying hen","free range (litter floor)"]
["Laying hen","free range (grating floor)"]
["Turkey"," - "]
["Horse"," - "]
["Rabbit"," - "]
["Description of Exposure Models/\nAssumptions"]
["Calculation"]
["Parameters/\nDefault Values"]
[]
[]
[]
[]
[]
[]
[]
["Total Estimated Livestock Exposure (mg a.s./kg bw/d)"]
["Sum of all scenarios checked above"]
[]
["Animal Species"]
["Beef cattle"," - "]
["Dairy cattle"," - "]
["Calf"," - "]
["Fattening pig"," - "]
["Breeding pig"," - "]
["Breeding pig","individual housing"]
["Breeding pig","group housing"]
["Sheep"," - "]
["Lamb"," - "]
["Slaughter goat"," - "]
["Lactating goat"," - "]
["Broilers"," - "]
["Broilers","free range, litter floor"]
["Broilers","parent broilers, free range (grating floor)"]
["Broilers","parent broilers in rearing, free range (grating floor)"]
["Laying hen"," - "]
["Laying hen","battery"]
["Laying hen","free range (litter floor)"]
["Laying hen","free range (grating floor)"]
["Turkey"," - "]
["Horse"," - "]
["Rabbit"," - "]
["Please note that some scenarios for chicken and pigs distinguish between several housing conditions. "]
[]
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[]
[]
["Product types"]
["PT1 - Human hygiene biocidal products"]
["PT2 - Private area and public health area disinfectants and other biocidal products"]
["PT3 - Veterinary hygiene biocidal products"]
["PT4 - Food and feed area disinfectants"]
["PT5 - Drinking water disinfectants"]
["PT6 - In-can preservatives"]
["PT7 - Film preservatives"]
["PT8 - Wood preservatives"]
["PT9 - Fibre, leather, rubber and polymerised materials preservatives"]
["PT10 - Masonry preservatives"]
["PT11 - Preservatives for liquid-cooling and processing systems"]
["PT12 - Slimicides"]
["PT13 - Metalworking-fluid preservatives"]
["PT14 - Rodenticides"]
["PT15 - Avicides"]
["PT16 - Molluscicides"]
["PT17 - Piscicides"]
["PT18 - Insecticides, acaricides and products to control other arthropods"]
["PT19 - Repellents and attractants"]
["PT20 - Preservatives for food or feedstocks"]
["PT21 - Antifouling products"]
["PT22 - Embalming and taxidermist fluids"]
["PT23 - Control of other vertebrates"]
["<choose product type>"]
[]
["Type of product application"]
["spray"]
["fogging"]
["nebulising"]
["fumigation"]
["vaporizer"]
["brush application"]
["granule application"]
["dusting powder"]
["bait station"]
["other"]
["<choose type of application>"]
[]
["Concentration of a.s. in biocidal product"]
["mg/kg"]
["mg/L"]
["% (w/w)"]
["% (v/v)"]
["mg/unit (ear tag, bait station etc)"]
["<choose unit>"]

{"sheet":"Report (WCCE)","index":4,"n_rows":117,"n_cols":9,"rows_kept":117,"cut":false,"hidden":false,"merged":[[28,7,29,7],[28,8,29,8],[28,0,29,0],[30,0,31,0],[33,7,34,7],[33,8,34,8],[30,7,31,7],[30,8,31,8],[26,0,27,0],[24,0,25,0],[17,0,17,13],[15,0,15,13],[16,0,16,13],[18,0,18,13],[24,7,25,7],[24,8,25,8],[67,0,68,0],[67,7,68,7],[67,8,68,8],[54,0,54,13],[33,0,34,0],[52,0,52,13],[53,0,53,13],[8,0,8,13],[62,0,63,0],[62,7,63,7],[62,8,63,8],[64,0,65,0],[64,7,65,7],[64,8,65,8],[58,0,59,0],[58,7,59,7],[58,8,59,8],[60,0,61,0],[60,7,61,7],[60,8,61,8],[26,7,27,7],[26,8,27,8],[21,0,21,6]]}
["Input"]
["*If ARfD is not considered necessary leave blank. If the ARfD has not been assessed enter ADI.\n\n\n"]
[]
[null,null,null,"Unit","Source"]
[null,"ADI",null,"mg/kg bw/day"]
[null,"ARfD*",null,"mg/kg bw/day"]
[]
["Refined WCCE using empirical transfer factors based on the octanol–water partition coefficient (log POW)"]
["Empirical transfer factors (TF) based on the Octanol–Water Partition Coefficient (log P_O/W) may be considered to estimate the maximum transfer of an external oral dose to livestock edible tissues (see Leeman et al. 2007). The factors are applicable for oral uptake only. For an overview of all TF defaults see table \"Defaults 6 LogP_OW\"."]
[]
[null,"log POW range","< choose a logPOW range >"]
[]
[]
[]
["Report for Worst Case Consumer Exposure  [mg/kg bw/d]"]
["The evaluation of the worst-case consumer exposure (WCCE) is described in detail in the EMA-CVMP \"Guideline on risk characterisation and assessment of maximum residue limits (MRL) for biocides\".   "]
["The WCCE is calculated for five different cases: 1. the EMA standard food basket and 2.-5. the EFSA PRIMo v3.1 consumption data set (chronic, acute, adult, child). For each case the WCCE is calculated for the following food commodities of animal origin: muscle, fat, liver, kidney, milk and eggs. For the acute exposure estimation, the WCCE for each commodity should be compared the acute reference dose (ARfD) of the active substance. For the chronic exposure estimation, all commodities are added up to estimate the total WCCE, which should be compared to the acceptable daily intake (ADI) of the active substance."]
["Please note, that in this calculator the EMA standard food basket and the chronic EFSA PRIMo models cover only the a.s. intake via the biocidal use of the a.s.. There might be other exposure pathways to the a.s., such as via plant products when used as pesticide. If this is the case, all routes of exposure need to be considered to estimate a correct chronic WCCE (see also EFSA website for PRIMo model with all available food commodities)."]
["If the total WCCE is > 30% of the ADI/ARfD and/or in case there is a particular concern in relation to toxicity, use of the active substance may represent a consumer safety concern and a maximum residue limit (MRL) evaluation may be required."]
[]
["WCCE = ((transfer factor (based on log PO/W) x oral exposure) + dermal exposure + inhalative exposure) x food intake per day ÷ human body weight"]
["WCCEtotal=WCCEmuscle + WCCEfat + WCCEliver + WCCEkidney + WCCEmilk + WCCEeggs"]
[]
[null,"WCCEmuscle","WCCEfat","WCCEliver","WCCEkidney","WCCEmilk","WCCEeggs","WCCEtotal ","% of ADI (chronic) "]
["EMA Food Basket",{"$f":"MAX('Calc (WCCE)'!$G$22,'Calc (WCCE)'!$G$28,'Calc (WCCE)'!$G$33,'Calc (WCCE)'!$G$39,'Calc (WCCE)'!$G$45,'Calc (WCCE)'!$G$51)","v":0},{"$f":"MAX('Calc (WCCE)'!$G$23,'Calc (WCCE)'!$G$29,'Calc (WCCE)'!$G$34,'Calc (WCCE)'!$G$40,'Calc (WCCE)'!$G$46,'Calc (WCCE)'!$G$52)","v":0},{"$f":"MAX('Calc (WCCE)'!$G$24,'Calc (WCCE)'!$G$30,'Calc (WCCE)'!$G$35,'Calc (WCCE)'!$G$41,'Calc (WCCE)'!$G$47,'Calc (WCCE)'!$G$53)","v":0},{"$f":"MAX('Calc (WCCE)'!$G$25,'Calc (WCCE)'!$G$31,'Calc (WCCE)'!$G$36,'Calc (WCCE)'!$G$42,'Calc (WCCE)'!$G$48,'Calc (WCCE)'!$G$54)","v":0},{"$f":"MAX('Calc (WCCE)'!$G$26,'Calc (WCCE)'!$G$37,'Calc (WCCE)'!$G$43)","v":0},{"$f":"'Calc (WCCE)'!$G$49","v":0},{"$f":"SUM(B25:G25)","v":0},{"$f":"(100/$C$5)*H25","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!B25,'Calc (WCCE)'!$G$21:$G$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!C25,'Calc (WCCE)'!$G$21:$G$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!D25,'Calc (WCCE)'!$G$21:$G$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!E25,'Calc (WCCE)'!$G$21:$G$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$43,MATCH('Report (WCCE)'!F25,'Calc (WCCE)'!$G$21:$G$43,0))","v":"Bovine"},"Laying hen"]
["EFSA PRIMo\n- chronic\n- adult",{"$f":"MAX('Calc (WCCE)'!$C$22,'Calc (WCCE)'!$C$28,'Calc (WCCE)'!$C$33,'Calc (WCCE)'!$C$39,'Calc (WCCE)'!$C$45,'Calc (WCCE)'!$C$51)","v":0},{"$f":"MAX('Calc (WCCE)'!$C$23,'Calc (WCCE)'!$C$29,'Calc (WCCE)'!$C$34,'Calc (WCCE)'!$C$40,'Calc (WCCE)'!$C$46,'Calc (WCCE)'!$C$52)","v":0},{"$f":"MAX('Calc (WCCE)'!$C$24,'Calc (WCCE)'!$C$30,'Calc (WCCE)'!$C$35,'Calc (WCCE)'!$C$41,'Calc (WCCE)'!$C$47,'Calc (WCCE)'!$C$53)","v":0},{"$f":"MAX('Calc (WCCE)'!$C$25,'Calc (WCCE)'!$C$31,'Calc (WCCE)'!$C$36,'Calc (WCCE)'!$C$42,'Calc (WCCE)'!$C$48,'Calc (WCCE)'!$C$54)","v":0},{"$f":"MAX('Calc (WCCE)'!$C$26,'Calc (WCCE)'!$C$37,'Calc (WCCE)'!$C$43)","v":0},{"$f":"'Calc (WCCE)'!$C$49","v":0},{"$f":"SUM(B27:G27)","v":0},{"$f":"(100/$C$5)*H27","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!B27,'Calc (WCCE)'!$C$21:$C$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!C27,'Calc (WCCE)'!$C$21:$C$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!D27,'Calc (WCCE)'!$C$21:$C$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!E27,'Calc (WCCE)'!$C$21:$C$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$43,MATCH('Report (WCCE)'!F27,'Calc (WCCE)'!$C$21:$C$43,0))","v":"Bovine"},"Laying hen"]
["EFSA PRIMo\n- chronic\n- child",{"$f":"MAX('Calc (WCCE)'!$D$22,'Calc (WCCE)'!$D$28,'Calc (WCCE)'!$D$33,'Calc (WCCE)'!$D$39,'Calc (WCCE)'!$D$45,'Calc (WCCE)'!$D$51)","v":0},{"$f":"MAX('Calc (WCCE)'!$D$23,'Calc (WCCE)'!$D$29,'Calc (WCCE)'!$D$34,'Calc (WCCE)'!$D$40,'Calc (WCCE)'!$D$46,'Calc (WCCE)'!$D$52)","v":0},{"$f":"MAX('Calc (WCCE)'!$D$24,'Calc (WCCE)'!$D$30,'Calc (WCCE)'!$D$35,'Calc (WCCE)'!$D$41,'Calc (WCCE)'!$D$47,'Calc (WCCE)'!$D$53)","v":0},{"$f":"MAX('Calc (WCCE)'!$D$25,'Calc (WCCE)'!$D$31,'Calc (WCCE)'!$D$36,'Calc (WCCE)'!$D$42,'Calc (WCCE)'!$D$48,'Calc (WCCE)'!$D$54)","v":0},{"$f":"MAX('Calc (WCCE)'!$D$26,'Calc (WCCE)'!$D$37,'Calc (WCCE)'!$D$43)","v":0},{"$f":"'Calc (WCCE)'!$D$49","v":0},{"$f":"SUM(B29:G29)","v":0},{"$f":"(100/$C$5)*H29","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!B29,'Calc (WCCE)'!$D$21:$D$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!C29,'Calc (WCCE)'!$D$21:$D$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!D29,'Calc (WCCE)'!$D$21:$D$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!E29,'Calc (WCCE)'!$D$21:$D$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$43,MATCH('Report (WCCE)'!F29,'Calc (WCCE)'!$D$21:$D$43,0))","v":"Bovine"},"Laying hen"]
["EFSA PRIMo\n- acute\n- adult",{"$f":"MAX('Calc (WCCE)'!$E$22,'Calc (WCCE)'!$E$28,'Calc (WCCE)'!$E$33,'Calc (WCCE)'!$E$39,'Calc (WCCE)'!$E$45,'Calc (WCCE)'!$E$51)","v":0},{"$f":"MAX('Calc (WCCE)'!$E$23,'Calc (WCCE)'!$E$29,'Calc (WCCE)'!$E$34,'Calc (WCCE)'!$E$40,'Calc (WCCE)'!$E$46,'Calc (WCCE)'!$E$52)","v":0},{"$f":"MAX('Calc (WCCE)'!$E$24,'Calc (WCCE)'!$E$30,'Calc (WCCE)'!$E$35,'Calc (WCCE)'!$E$41,'Calc (WCCE)'!$E$47,'Calc (WCCE)'!$E$53)","v":0},{"$f":"MAX('Calc (WCCE)'!$E$25,'Calc (WCCE)'!$E$31,'Calc (WCCE)'!$E$36,'Calc (WCCE)'!$E$42,'Calc (WCCE)'!$E$48,'Calc (WCCE)'!$E$54)","v":0},{"$f":"MAX('Calc (WCCE)'!$E$26,'Calc (WCCE)'!$E$37,'Calc (WCCE)'!$E$43)","v":0},{"$f":"'Calc (WCCE)'!$E$49","v":0}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!B31,'Calc (WCCE)'!$E$21:$E$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!C31,'Calc (WCCE)'!$E$21:$E$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!D31,'Calc (WCCE)'!$E$21:$E$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!E31,'Calc (WCCE)'!$E$21:$E$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$43,MATCH('Report (WCCE)'!F31,'Calc (WCCE)'!$E$21:$E$43,0))","v":"Bovine"},"Laying hen"]
["% ARfD (acute)",{"$f":"(100/$C$6)*B31","v":{"$error":"#DIV/0!"}},{"$f":"(100/$C$6)*C31","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["EFSA PRIMo\n- acute\n- child",{"$f":"MAX('Calc (WCCE)'!$F$22,'Calc (WCCE)'!$F$28,'Calc (WCCE)'!$F$33,'Calc (WCCE)'!$F$39,'Calc (WCCE)'!$F$45,'Calc (WCCE)'!$F$51)","v":0},{"$f":"MAX('Calc (WCCE)'!$F$23,'Calc (WCCE)'!$F$29,'Calc (WCCE)'!$F$34,'Calc (WCCE)'!$F$40,'Calc (WCCE)'!$F$46,'Calc (WCCE)'!$F$52)","v":0},{"$f":"MAX('Calc (WCCE)'!$F$24,'Calc (WCCE)'!$F$30,'Calc (WCCE)'!$F$35,'Calc (WCCE)'!$F$41,'Calc (WCCE)'!$F$47,'Calc (WCCE)'!$F$53)","v":0},{"$f":"MAX('Calc (WCCE)'!$F$25,'Calc (WCCE)'!$F$31,'Calc (WCCE)'!$F$36,'Calc (WCCE)'!$F$42,'Calc (WCCE)'!$F$48,'Calc (WCCE)'!$F$54)","v":0},{"$f":"MAX('Calc (WCCE)'!$F$26,'Calc (WCCE)'!$F$37,'Calc (WCCE)'!$F$43)","v":0},{"$f":"'Calc (WCCE)'!$F$49","v":0}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!B34,'Calc (WCCE)'!$F$21:$F$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!C34,'Calc (WCCE)'!$F$21:$F$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!D34,'Calc (WCCE)'!$F$21:$F$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$54,MATCH('Report (WCCE)'!E34,'Calc (WCCE)'!$F$21:$F$54,0))","v":"Bovine"},{"$f":"INDEX('Calc (WCCE)'!$A$21:$A$43,MATCH('Report (WCCE)'!F34,'Calc (WCCE)'!$F$21:$F$43,0))","v":"Bovine"},"Laying hen"]
["% ARfD (acute)",{"$f":"(100/$C$6)*B34","v":{"$error":"#DIV/0!"}},{"$f":"(100/$C$6)*C34","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[]
[]
["Animal species with highest exposure (RWCE) taken for worst-case calculations"]
[]
["Animal group","Animal species","Housing type"]
["Bovine",{"$f":"'Calc (WCCE)'!B7","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C7","v":{"$error":"#N/A"}}]
["Pig",{"$f":"'Calc (WCCE)'!B8","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C8","v":{"$error":"#N/A"}}]
["Sheep",{"$f":"'Calc (WCCE)'!B9","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C9","v":{"$error":"#N/A"}}]
["Goat",{"$f":"'Calc (WCCE)'!B10","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C10","v":{"$error":"#N/A"}}]
["Horse",{"$f":"'Calc (WCCE)'!B12","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C12","v":{"$error":"#N/A"}}]
["Milk producing animals",{"$f":"'Calc (WCCE)'!B14","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!C14","v":{"$error":"#N/A"}}]
["Egg producing animals","Laying hen",{"$f":"'Calc (WCCE)'!C15","v":{"$error":"#N/A"}}]
["Please note that some scenarios for chicken and pigs distinguish between several housing conditions (see Report (Realistic worst case))"]
[]
[]
["Worst Case Consumer Exposure refined with empirical transfer factors based on log PO/W [mg/kg bw/d]"]
["Initially it is assumed that the estimated external livestock exposure reflects the internal livestock exposure.\nEmpirical transfer factors (TF) based on the Octanol–Water Partition Coefficient (log P_O/W) may be considered to estimate the maximum transfer of an external oral dose to livestock edible tissues (see Leeman et al. 2007). The factors are applicable for oral uptake only."]
["TFs are included in the calculations as follows: Residues in animal tissue = Exposure_oral x TF_tissue + Exposure_dermal + Exposure_inhalative"]
[]
[]
[null,"WCCEmuscle","WCCEfat","WCCEliver","WCCEkidney","WCCEmilk","WCCEeggs","WCCEtotal ","% of ADI (chronic) / ARfD (acute)"]
["EMA Food Basket",{"$f":"MAX('Calc (WCCE)'!$G$95,'Calc (WCCE)'!$G$101,'Calc (WCCE)'!$G$106,'Calc (WCCE)'!$G$112,'Calc (WCCE)'!$G$118,'Calc (WCCE)'!$G$124)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$G$96,'Calc (WCCE)'!$G$102,'Calc (WCCE)'!$G$107,'Calc (WCCE)'!$G$113,'Calc (WCCE)'!$G$119,'Calc (WCCE)'!$G$125)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$G$97,'Calc (WCCE)'!$G$103,'Calc (WCCE)'!$G$108,'Calc (WCCE)'!$G$114,'Calc (WCCE)'!$G$120,'Calc (WCCE)'!$G$126)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$G$98,'Calc (WCCE)'!$G$104,'Calc (WCCE)'!$G$109,'Calc (WCCE)'!$G$115,'Calc (WCCE)'!$G$121,'Calc (WCCE)'!$G$127)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$G$99,'Calc (WCCE)'!$G$110,'Calc (WCCE)'!$G$116)","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!$G$122","v":{"$error":"#N/A"}},{"$f":"SUM(B59:G59)","v":{"$error":"#N/A"}},{"$f":"(100/$C$5)*H59","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!B59,'Calc (WCCE)'!$G$95:$G$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!C59,'Calc (WCCE)'!$G$95:$G$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!D59,'Calc (WCCE)'!$G$95:$G$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!E59,'Calc (WCCE)'!$G$95:$G$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$116,MATCH('Report (WCCE)'!F59,'Calc (WCCE)'!$G$95:$G$116,0))","v":{"$error":"#N/A"}},"Laying hen"]
["EFSA PRIMo\n- chronic\n- adult",{"$f":"MAX('Calc (WCCE)'!$C$95,'Calc (WCCE)'!$C$101,'Calc (WCCE)'!$C$106,'Calc (WCCE)'!$C$112,'Calc (WCCE)'!$C$118,'Calc (WCCE)'!$C$124)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$C$96,'Calc (WCCE)'!$C$102,'Calc (WCCE)'!$C$107,'Calc (WCCE)'!$C$113,'Calc (WCCE)'!$C$119,'Calc (WCCE)'!$C$125)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$C$97,'Calc (WCCE)'!$C$103,'Calc (WCCE)'!$C$108,'Calc (WCCE)'!$C$114,'Calc (WCCE)'!$C$120,'Calc (WCCE)'!$C$126)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$C$98,'Calc (WCCE)'!$C$104,'Calc (WCCE)'!$C$109,'Calc (WCCE)'!$C$115,'Calc (WCCE)'!$C$121,'Calc (WCCE)'!$C$127)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$C$99,'Calc (WCCE)'!$C$110,'Calc (WCCE)'!$C$116)","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!$C$122","v":{"$error":"#N/A"}},{"$f":"SUM(B61:G61)","v":{"$error":"#N/A"}},{"$f":"(100/$C$5)*H61","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!B61,'Calc (WCCE)'!$C$95:$C$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!C61,'Calc (WCCE)'!$C$95:$C$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!D61,'Calc (WCCE)'!$C$95:$C$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!E61,'Calc (WCCE)'!$C$95:$C$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$116,MATCH('Report (WCCE)'!F61,'Calc (WCCE)'!$C$95:$C$116,0))","v":{"$error":"#N/A"}},"Laying hen"]
["EFSA PRIMo\n- chronic\n- child",{"$f":"MAX('Calc (WCCE)'!$D$95,'Calc (WCCE)'!$D$101,'Calc (WCCE)'!$D$106,'Calc (WCCE)'!$D$112,'Calc (WCCE)'!$D$118,'Calc (WCCE)'!$D$124)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$D$96,'Calc (WCCE)'!$D$102,'Calc (WCCE)'!$D$107,'Calc (WCCE)'!$D$113,'Calc (WCCE)'!$D$119,'Calc (WCCE)'!$D$125)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$D$97,'Calc (WCCE)'!$D$103,'Calc (WCCE)'!$D$108,'Calc (WCCE)'!$D$114,'Calc (WCCE)'!$D$120,'Calc (WCCE)'!$D$126)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$D$98,'Calc (WCCE)'!$D$104,'Calc (WCCE)'!$D$109,'Calc (WCCE)'!$D$115,'Calc (WCCE)'!$D$121,'Calc (WCCE)'!$D$127)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$D$99,'Calc (WCCE)'!$D$110,'Calc (WCCE)'!$D$116)","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!$D$122","v":{"$error":"#N/A"}},{"$f":"SUM(B63:G63)","v":{"$error":"#N/A"}},{"$f":"(100/$C$5)*H63","v":{"$error":"#DIV/0!"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!B63,'Calc (WCCE)'!$D$95:$D$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!C63,'Calc (WCCE)'!$D$95:$D$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!D63,'Calc (WCCE)'!$D$95:$D$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!E63,'Calc (WCCE)'!$D$95:$D$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$116,MATCH('Report (WCCE)'!F63,'Calc (WCCE)'!$D$95:$D$116,0))","v":{"$error":"#N/A"}},"Laying hen"]
["EFSA PRIMo\n- acute\n- adult",{"$f":"MAX('Calc (WCCE)'!$E$95,'Calc (WCCE)'!$E$101,'Calc (WCCE)'!$E$106,'Calc (WCCE)'!$E$112,'Calc (WCCE)'!$E$118,'Calc (WCCE)'!$E$124)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$E$96,'Calc (WCCE)'!$E$102,'Calc (WCCE)'!$E$107,'Calc (WCCE)'!$E$113,'Calc (WCCE)'!$E$119,'Calc (WCCE)'!$E$125)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$E$97,'Calc (WCCE)'!$E$103,'Calc (WCCE)'!$E$108,'Calc (WCCE)'!$E$114,'Calc (WCCE)'!$E$120,'Calc (WCCE)'!$E$126)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$E$98,'Calc (WCCE)'!$E$104,'Calc (WCCE)'!$E$109,'Calc (WCCE)'!$E$115,'Calc (WCCE)'!$E$121,'Calc (WCCE)'!$E$127)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$E$99,'Calc (WCCE)'!$E$110,'Calc (WCCE)'!$E$116)","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!$E$122","v":{"$error":"#N/A"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!B65,'Calc (WCCE)'!$E$95:$E$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!C65,'Calc (WCCE)'!$E$95:$E$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!D65,'Calc (WCCE)'!$E$95:$E$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!E65,'Calc (WCCE)'!$E$95:$E$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$116,MATCH('Report (WCCE)'!F65,'Calc (WCCE)'!$E$95:$E$116,0))","v":{"$error":"#N/A"}},"Laying hen"]
["% ARfD (acute)",{"$f":"(100/$C$6)*B65","v":{"$error":"#DIV/0!"}},{"$f":"(100/$C$6)*C65","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["EFSA PRIMo\n- acute\n- child",{"$f":"MAX('Calc (WCCE)'!$F$95,'Calc (WCCE)'!$F$101,'Calc (WCCE)'!$F$106,'Calc (WCCE)'!$F$112,'Calc (WCCE)'!$F$118,'Calc (WCCE)'!$F$124)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$F$96,'Calc (WCCE)'!$F$102,'Calc (WCCE)'!$F$107,'Calc (WCCE)'!$F$113,'Calc (WCCE)'!$F$119,'Calc (WCCE)'!$F$125)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$F$97,'Calc (WCCE)'!$F$103,'Calc (WCCE)'!$F$108,'Calc (WCCE)'!$F$114,'Calc (WCCE)'!$F$120,'Calc (WCCE)'!$F$126)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$F$98,'Calc (WCCE)'!$F$104,'Calc (WCCE)'!$F$109,'Calc (WCCE)'!$F$115,'Calc (WCCE)'!$F$121,'Calc (WCCE)'!$F$127)","v":{"$error":"#N/A"}},{"$f":"MAX('Calc (WCCE)'!$F$99,'Calc (WCCE)'!$F$110,'Calc (WCCE)'!$F$116)","v":{"$error":"#N/A"}},{"$f":"'Calc (WCCE)'!$F$122","v":{"$error":"#N/A"}}]
[null,{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!B68,'Calc (WCCE)'!$F$95:$F$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!C68,'Calc (WCCE)'!$F$95:$F$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!D68,'Calc (WCCE)'!$F$95:$F$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$127,MATCH('Report (WCCE)'!E68,'Calc (WCCE)'!$F$95:$F$127,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Calc (WCCE)'!$A$95:$A$116,MATCH('Report (WCCE)'!F68,'Calc (WCCE)'!$F$95:$F$116,0))","v":{"$error":"#N/A"}},"Laying hen"]
["% ARfD (acute)",{"$f":"(100/$C$6)*B68","v":{"$error":"#DIV/0!"}},{"$f":"(100/$C$6)*C68","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
["Log POW range"]
["< choose a logPOW range >"]
["<0"]
["0–1"]
["1–2"]
["2–3"]
["3–4"]
["4–5"]
["5–6"]
["6–7"]
["7–8"]
[">8"]
["Metals total"]

{"sheet":"Calc (Screening)","index":5,"n_rows":37,"n_cols":25,"rows_kept":37,"cut":false,"hidden":false,"merged":[]}
["Screening (mg a.s./kg bw/d)"]
["The screening step assumes that the entire amount of biocidal product applied is taken up by animals regardless of the route of exposure."]
[]
["Animal Species",null,"Surface treatment of animal housing","Surface treatment of animal housing (floor&wall of stable without partitions)","Surface treatment of animal housing (floor only)","Surface treatment of animal housing (wall only)","Space treatment of animal housing","Surface treatment of transport vehicles","Space treatment of transport vehicles","Treatment of feed","Treatment of drinking water ","Surface treatment of storage facilities for feedstuff (silo type #1)","Surface treatment of storage facilities for feedstuff (silo type #2)","Surface treatment of storage facilities for feedstuff (silo type #3)","Surface treatment of storage facilities for feedstuff (silo type #4)","Space treatment of storage facilities for feedstuff (silo type #1)","Space treatment of storage facilities for feedstuff (silo type #2)","Space treatment of storage facilities for feedstuff (silo type #3)","Space treatment of storage facilities for feedstuff (silo type #4)","Direct treatment of livestock animals -  teat dip (dermal absorption)","Direct treatment of livestock animals -  teat dip (residues in milk)","Direct treatment of livestock animals - hoof disinfection","Direct treatment of livestock animals -   ear tags","Direct exposure of an individual livestock animal ","Treatment of packaging material for feed"]
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["Dairy cattle",null,{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!E7/'Defaults 2'!C7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!D7/'Defaults 2'!C7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*('Defaults 2'!E7-'Defaults 2'!D7)/'Defaults 2'!C7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!F7/'Defaults 2'!C7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$35/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$35/20","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$55/'Defaults 2'!C7/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$39/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B7","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J7/'Defaults 1'!B7","v":0}]
["Calf",null,{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!E8/'Defaults 2'!C8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!D8/'Defaults 2'!C8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*('Defaults 2'!E8-'Defaults 2'!D8)/'Defaults 2'!C8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!F8/'Defaults 2'!C8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J8/'Defaults 1'!B8","v":0},null,null,{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$55/'Defaults 2'!C8/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$39/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B8","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J8/'Defaults 1'!B8","v":0}]
["Fattening pig",null,{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!E9/'Defaults 2'!C9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!D9/'Defaults 2'!C9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*('Defaults 2'!E9-'Defaults 2'!D9)/'Defaults 2'!C9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!F9/'Defaults 2'!C9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J9/'Defaults 1'!B9","v":0},null,null,null,null,{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B9","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J9/'Defaults 1'!B9","v":0}]
["Breeding pig",null,null,null,null,null,null,{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J10/'Defaults 1'!B10","v":0},null,null,null,null,{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B10","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J10/'Defaults 1'!B10","v":0}]
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["Turkey",null,null,null,null,null,null,{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J17/'Defaults 1'!B17","v":0},null,null,null,null,{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B17","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J17/'Defaults 1'!B17","v":0}]
["Horse",null,null,null,null,null,null,{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J18/'Defaults 1'!B18","v":0},null,null,null,null,{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B18","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J18/'Defaults 1'!B18","v":0}]
["Rabbit",null,{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!J24/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!E24/'Defaults 2'!C24/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!D24/'Defaults 2'!C24/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*('Defaults 2'!E24-'Defaults 2'!D24)/'Defaults 2'!C24/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 2'!F24/'Defaults 2'!C24/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!L19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 3'!M19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 1'!K19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$13/('Defaults 4'!$C$12*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$18/('Defaults 4'!$C$17*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$23/('Defaults 4'!$C$22*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$28/('Defaults 4'!$C$27*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$9/('Defaults 4'!$C$12*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$14/('Defaults 4'!$C$17*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$19/('Defaults 4'!$C$22*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*'Defaults 4'!$C$24/('Defaults 4'!$C$27*1000)*'Defaults 1'!J19/'Defaults 1'!B19","v":0},null,null,null,null,{"$f":"'Report (Screening)'!$C$15/'Defaults 1'!B19","v":0},{"$f":"'Report (Screening)'!$C$15*1000*'Defaults 4'!$C$30/'Defaults 4'!$C$31*0.1/0.9*'Defaults 4'!$C$32*'Defaults 4'!$C$33/1000000*1*'Defaults 1'!J19/'Defaults 1'!B19","v":0}]
["Description of Exposure Model/\nAssumptions",null,"All surfaces of the animal housing are treated with the biocidal product. This model considers the maximum wall and floor area within reach of animal, taking into account that the individual animal is surrounded by 3-4 walls (see default table 2)","Complete wall and floor areas  of animal housing (without partitions) are treated with the biocidal product.","Floor area of animal housing is treated with the biocidal product. ","Wall area of animal housing is treated with the biocidal product. ","The complete volume of the animal housing is treated with the biocidal product, e.g. by fogging, nebulising application etc.. Biocide residues are assumed to be distributed evenly throughout the airspace. No room ventilation is considered.","All surfaces within a transport vehicle are disinfected with the biocidal product. The model considers a truck of 7.0 m x 2.5 m with compartments as described in Annex I, Table 3 of the TNsG. ","The complete volume of a transport vehicle is treated with the biocidal product, e.g. by fogging, nebulising application etc. The model considers a truck of 7.0 m x 2.5 m with compartments as described in Annex I, Table 3 of the TNsG. ","Feed is treated with the biocidal product according to label instructions. Animals exclusively consume treated feed. ","Drinking water is treated with the biocidal product. Animals exclusively consume treated water. ","Surfaces of feed storage facility are treated with the biocidal product. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #1: surface 44,7 m2, \nholding capacity 5,7 t feed","Surfaces of feed storage facility are treated with the biocidal product. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #2: surface 72,7 m2, \nholding capacity 16 t feed","Surfaces of feed storage facility are treated with the biocidal product. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #2: surface 58,5 m2,\nholding capacity 10,8 t feed","Surfaces of feed storage facility are treated with the biocidal product. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #4: surface 36,8 m2, \nholding capacity 8,3 t feed","The whole volume of a feed storage facility is treated with the biocidal product, e.g. by fogging or nebulising. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #1: volume 13,56 m3, \nholding capacity 5,7 t","The whole volume of a feed storage facility is treated with the biocidal product, e.g. by fogging or nebulising. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #2: volume 26,62 m3, \nholding capacity 16 t","The whole volume of a feed storage facility is treated with a biocidal product, e.g. by fogging or nebulising. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #3: volume 18,0 m3, \nholding capacity 10,8 t","The whole volume of a feed storage facility is treated with the biocidal product, e.g. by fogging or nebulising. Calculation of this model for 4 different sizes of feed silos as given in  TNsG, Annex I, Table 4. \nFeed silo #4: volume 7,3 m3, \nholding capacity 8,3 t","Biocidal teat dip product is applied before or after each milking. In case of both, pre- and post-milking teat disinfection, this calculation needs to be performed twice.\n The model assumes 100 % dermal absorption and 2 milkings per day. The application rate is generally given by the applicant. In the absence of this information default values for applied volumes for various product formulations are available in Defaults 4. ","Biocidal teat dip product is applied before or after each milking. In case of both, pre- and post-milking teat disinfection, this calculation needs to be performed twice.\n The model estimated residues in milk through contamination during milking. It assumes 0 % dermal absorption and 2 milkings per day. The application rate is generally given by the applicant. In the absence of this information default values for applied volumes for various product formulations are available in Defaults 4. \nThe estimated residues in milk should not be compared with the trigger value of 0.004 mg a.s./kg bw/d but rather a WCCE should be calculated.","Animals are exposed to the total amount of active substance contained in the hoof bath tub located at the stable exit/entrance. ","The animal is exposed to the total amount of active substance contained in 2 ear tags. ","An individual animal is exposed to a specified amount of biocidal product, e.g. neck collar containing an active substance etc .","Packaging material for feedstuff has been treated with the biocidal product. The OECD ESD assumes that 90 % of the a.s. is lost in waste water and 10 % remains in the paper during paper production. Furthermore, it is assumed that 100 % of the active substance migrates from the material into the feed. 100 % of the animals´ daily feed consumption is from this contaminated feed. According to the EU Notes for Guidance for Food Contact Materials prepared by the European Food Safety Authority, it can be estimated that 1 kg of feed is in contact with 600 cm² of food packaging."]
["Calculation",null,"Exposure=AR*Areach/bw","Exposure=AR*Aw+f/Noanim/bw","Exposure=AR*Af/Noanim/bw","Exposure=AR*(Aw+f - Af)/Noanim/bw","Exposure=AR*Vstable/Noanim/bw","Exposure=AR*Aw+f/bw","Exposure=AR*Vanim/bw","Exposure=AR*FC/bw","Exposure=AR*WC/bw","Exposure=AR*Asilo#1/HCsilo#1*FC/bw","Exposure=AR*Asilo#2/HCsilo#2*FC/bw","Exposure=AR*Asilo#3/HCsilo#3*FC/bw","Exposure=AR*Asilo#4/HCsilo#4*FC/bw","Exposure=AR*Vsilo#1/HCsilo#1*FC/bw","Exposure=AR*Vsilo#2/HCsilo#2*FC/bw","Exposure=AR*Vsilo#3/HCsilo#3*FC/bw","Exposure=AR*Vsilo#4/HCsilo#4*FC/bw","Exposure=AR*Nomilkings/bw","Exposure=AR*Nomilkings/Vmilk","Exposure=AR*Vtub/Noanim/bw","Exposure=AR*Noeartag/bw","Exposure=AR/bw","Exposure= (AR * V_WW *1000 * 0.1 / 0.9 / PP) * (M_dry_paper * A_dry_paper / M_feed) * F_packaged * FC / bw"]
["Parameters/\nDefault values",null,"AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m3)","AR: Application rate (mg/m2)","AR: Application rate (mg/m3)","AR: Application rate (mg/kg feed)","AR: Application rate (mg/L)","AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m2)","AR: Application rate (mg/m3)","AR: Application rate (mg/m3)","AR: Application rate (mg/m3)","AR: Application rate (mg/m3)","AR: Application rate (mg/animal per milking) AR=VBP x fBP x Ca.s.\nVBP: Product volume on teats per milking (default=10 mL/milking/animal, Defaults 4)\nfBP: fraction of biocidal product remaining on teats (default=0.5, according to OECD ESD for PT3)\nCa.s.: concentration of active substance in product (mg/ml)","AR: Application rate (mg/animal per milking) AR=VBP x fBP x Ca.s.\nVBP: Product volume on teats per milking (default: 10 mL/milking for 4 teats)\nfBP: fraction of biocidal product remaining on teats (default=0.5, according to OECD ESD for PT3)\nCa.s.: concentration of active substance in product (mg/ml)","AR: Application rate (mg /L hoof bath)","AR: Application rate (mg/ear tag)","AR: Application rate (mg/animal)","AR: Application rate (mg/L = g/m³)"]
[null,null,"Areach: maximal area within reach of animal, wall+floor (m2)\n(Defaults 2)","Aw+f: wall+floor area per stable (m2)\n(Defaults 2)","Af: floor area per stable (m2)\n(Defaults 2)","Aw: wall area per stable (m2)\n(Defaults 2)","Vstable: animal housing volume per stable (m³) (Defaults 2)","Aw+f: available floor+wall area in transport vehicle per animal (m²) (Defaults 3)","Vanim: available volume per animal (m³) (Defaults 3)","FC: daily feed consumption per animal (kg) (Defaults 1)","WC: daily water consumption per animal (L) (Defaults 1)","Asilo#1: silo surface area \n(default=44,7 m², Defaults 4)","Asilo#2: silo surface area \n(default=72,7 m², Defaults 4)","Asilo#3: silo surface area \n(default=58,5 m², Defaults 4)","Asilo#4: silo surface area \n(default=36,8 m², Defaults 4)","Vsilo#1: silo volume (default= 13,56 m³, Defaults 4)","Vsilo#2: silo volume (default= 26,62 m³, Defaults 4)","Vsilo#3: silo volume (default= 18,0 m³, Defaults 4)","Vsilo#4: silo volume (default= 7,3 m³, Defaults 4)","Nomilkings: No. of milkings per day (default=2, Defaults 4)","Nomilkings: No. of milkings per day (default=2, Defaults 4)","Vtub: volume of tub for hoof bath (default=325 L, Defaults 4)","Noear tag: No of ear tags per animal (default=2, Defaults 4)","bw: body weight (kg)\n(Defaults 1)","VWW: paper mill waste water (default=5000 m³, Defaults 4)"]
[null,null,"bw: body weight (kg)\n(Defaults 1)","Noanim: No. of animals per stable (Defaults 2)","Noanim: No. of animals per stable (Defaults 2)","Noanim: No. of animals per stable (Defaults 2)","Noanim: No. of animals per stable (Defaults 2)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","HCsilo#1: silo holding capacity (default=5,7 t feed, Defaults 4)","HCsilo#2: silo holding capacity (default=16 t feed, Defaults 4)","HCsilo#3: silo holding capacity (default=10,8 t feed, Defaults 4)","HCsilo#4: silo holding capacity (default=8,3 t feed, Defaults 4)","HCsilo#1: silo holding capacity (default=5,7 t feed, Defaults 4)","HCsilo#2: silo holding capacity (default=16 t feed, Defaults 4)","HCsilo#3: silo holding capacity (default=10,8 t feed, Defaults 4)","HCsilo#4: silo holding capacity (default=8,3 t feed, Defaults 4)","bw: body weight (kg)\n(Defaults 1)","Vmilk: daily milk yield  = 20 L/day\n(Defaults 4)","Noanim: No. of animals per stable (Defaults 2)","bw: body weight (kg)\n(Defaults 1)",null,"Fpackaged: fraction of feed packaged in treated material \n(default=1)"]
[null,null,null,"bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)",null,null,null,null,"FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)","FC: daily feed consumption per animal (kg) (Defaults 1)",null,null,"bw: body weight (kg)\n(Defaults 1)",null,null,"PP: daily paper production per mill (default=200 t/d, Defaults 4)"]
[null,null,null,null,null,null,null,null,null,null,null,"bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)",null,null,null,null,null,"Mdry_paper: dry paper weight (default=60 mg/cm², Defaults 4)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Mfeed: feed weight (default=1x106 mg, Defaults 4)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"Adry_paper: packaging surface in contact with 1 kg feed  (Defaults 4)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"FC: daily feed consumption per animal (kg) (Defaults 1)"]
[null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,"bw: body weight (kg)\n(Defaults 1)"]

{"sheet":"Calc (Realistic worst case)","index":6,"n_rows":102,"n_cols":9,"rows_kept":102,"cut":false,"hidden":false,"merged":[]}
["Realistic Worst-case Scenarios (mg a.s./kg bw/d)"]
[]
["Oral Scenarios"]
["Animal Species",null,"Oral - Animals licking surfaces","Oral - Uptake of feed (treatment of surfaces surrounding trough)","Oral - Uptake of feed (direct treatment of trough)","Oral - Uptake of feed contaminated  via packaging material","Oral - Chewing on wooden stall edgings","Oral - Ingestion of dead insects (poultry only)","Sum Oral"]
["Beef cattle"," - ",null,{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M6/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L6/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J6*'Defaults 4'!$C$34/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$18","v":0},null,null,{"$f":"SUM(C5:H5)","v":0}]
["Dairy cattle"," - ",null,{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M7/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L7/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J7*'Defaults 4'!$C$34/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$18","v":0},null,null,{"$f":"SUM(C6:H6)","v":0}]
["Calf"," - ",{"$f":"'Report (Realistic worst case)'!$C$15*'Defaults 4'!$C$43*'Defaults 4'!$C$44/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$15","v":0},{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M8/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L8/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J8*'Defaults 4'!$C$34/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Fattening pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$15*'Defaults 4'!$C$43*'Defaults 4'!$C$44/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$15","v":0},{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M9/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L9/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J9*'Defaults 4'!$C$34/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Breeding pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$15*'Defaults 4'!$C$43*'Defaults 4'!$C$44/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$15","v":0},null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$10*'Defaults 4'!$C$34/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Breeding pig","individual housing",{"$f":"'Report (Realistic worst case)'!$C$15*'Defaults 4'!$C$43*'Defaults 4'!$C$44/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$15","v":0},{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M10/'Defaults 1'!B10*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L10/'Defaults 1'!B10*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$10*'Defaults 4'!$C$34/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Breeding pig","group housing",{"$f":"'Report (Realistic worst case)'!$C$15*'Defaults 4'!$C$43*'Defaults 4'!$C$44/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$15","v":0},{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!M11/'Defaults 1'!B10*'Report (Realistic worst case)'!$E$16","v":0},{"$f":"'Report (Realistic worst case)'!$C$17*'Defaults 2'!L11/'Defaults 1'!B10*'Report (Realistic worst case)'!$E$17","v":0},{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$10*'Defaults 4'!$C$34/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Sheep"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J11*'Defaults 4'!$C$34/'Defaults 1'!B11*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Lamb"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J12*'Defaults 4'!$C$34/'Defaults 1'!B12*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Slaughter goat"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J13*'Defaults 4'!$C$34/'Defaults 1'!B13*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Lactating goat"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J14*'Defaults 4'!$C$34/'Defaults 1'!B14*'Report (Realistic worst case)'!$E$18","v":0},null,null,0]
["Broilers"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$15*'Defaults 4'!$C$34/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$20","v":0},0]
["Broilers","free range, litter floor",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$15*'Defaults 4'!$C$34/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$20","v":0},0]
["Broilers","parent broilers, free range (grating floor)",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$15*'Defaults 4'!$C$34/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$20","v":0},0]
["Broilers","parent broilers in rearing, free range (grating floor)",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$15*'Defaults 4'!$C$34/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$20","v":0},0]
["Laying hen"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$16*'Defaults 4'!$C$34/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$20","v":0},0]
["Laying hen","battery",null,{"$f":"'Report (Realistic worst case)'!$C$16*'Defaults 4'!$C$6*'Defaults 2'!$M$19/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$16","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$16*'Defaults 4'!$C$34/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$20","v":0},0]
["Laying hen","free range (litter floor)",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$16*'Defaults 4'!$C$34/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$20","v":0},0]
["Laying hen","free range (grating floor)",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!$J$16*'Defaults 4'!$C$34/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$20","v":0},0]
["Turkey"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J17*'Defaults 4'!$C$34/'Defaults 1'!B17*'Report (Realistic worst case)'!$E$18","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$20*'Defaults 4'!$C$42/'Defaults 1'!B17*'Report (Realistic worst case)'!E20","v":0},0]
["Horse"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J18*'Defaults 4'!$C$34/'Defaults 1'!B18*'Report (Realistic worst case)'!$E$18","v":0},{"$f":"'Report (Realistic worst case)'!$C$19*'Defaults 4'!C49/'Defaults 1'!B18*'Report (Realistic worst case)'!$E$19","v":0},null,0]
["Rabbit"," - ",null,null,null,{"$f":"'Report (Realistic worst case)'!$C$18*'Defaults 1'!J19*'Defaults 4'!$C$34/'Defaults 1'!B19*'Report (Realistic worst case)'!$E$18","v":0},{"$f":"'Report (Realistic worst case)'!$C$19*('Defaults 4'!C52/400000)/'Defaults 1'!B19*'Report (Realistic worst case)'!$E$19","v":0},null,0]
["Description of Exposure Models/\nAssumptions",null,"Animal are licking surfaces that were treated with the biocidal product. ","Troughs were not covered during biocidal spray treatment of surrounding animal housing walls, so that trough surfaces may be contaminated with the biocidal product. The model assumes that all residues contaminating the trough migrate into next feed batch which is consumed completely by the animal. ","Inner trough surfaces were treated with the biocidal product.  The model assumes that all residues on bottom and sides of trough migrate into next feed batch which is consumed completely by the animal. ","Packaging material for feedstuff has been treated with the biocidal product. This model assumes that 100% of the active substance migrates from the material into the feed.  10% of the animals´ daily feed consumption is from this contaminated feed.","Wood treated with the biocidal product is incorporated into stall edgings, livestock animals are exposed orally by chewing on the wood. ","The biocidal product is used as insecticide against flies. Chicken seek out dead flies for consumption. Each animal consumes 10 flies per day. "]
["Calculation",null,"Exposure=AR*Atongue*L/bw*RF","Exposure=AR*EF*Afeed surf/bw*RF","Exposure=AR*Afeed surf/bw*RF","Exposure=(AR * V_WW *1000 * 0.1 / 0.9 / PP) * (M_dry_paper * A_dry_paper / M_feed) * F_packaged * FC / bw*RF","Exposure=AR*Wood C/bw*RF","Exposure=AR*Nofly/bw*RF"]
["Parameters/\nDefault Values",null,"AR: application rate (mg/m2)","AR: application rate (mg/m2)","AR: application rate (mg/m2)","AR: application rate (mg/L)","AR: application rate (mg/m3)","AR: application rate (mg/fly/d)"]
[null,null,"Atongue: tongue surface area (default=0,008 m², Defaults 4)","EF: emission factor for spray application: fraction emitted to floor during surface treatment \n(default=0,11, Defaults 4)","Afeed surf: exposed feed surface \n(default for direct trough treatment, Defaults 2)","FC: daily feed consumption per animal (kg) (default, Defaults 1)","WoodC: wood consumption (m³) (rabbit: default in g, therefore division by wood densitity default=0,4 g/cm³, Defaults 4)","Nofly: fly consumption per animal (Defaults 4)"]
[null,null,"L: licks per day \n(default=10, Defaults 4)","Afeed surf: exposed feed surface \n(default for treatment of surfaces surrounding trough , Defaults 2)","bw: body weight (kg)\n(default, Defaults 1)","Fpackaged: fraction of feed packaged in treated material \n(default=10%, Defaults 4)","bw: body weight (kg)\n(default, Defaults 1)","bw: body weight (kg)\n(default, Defaults 1)"]
[null,null,"bw: body weight (kg)\n(default, Defaults 1)","bw: body weight (kg)\n(default, Defaults 1)","RF: refinement factor\n(default=1)","bw: body weight (kg)\n(default, Defaults 1)","RF: refinement factor\n(default=1)","RF: refinement factor\n(default=1)"]
[null,null,"RF: refinement factor\n(default=1)","RF: refinement factor\n(default=1)",null,"RF: refinement factor\n(default=1)"]
[]
[]
["Dermal Scenarios"]
["Animal Species",null,"Dermal - Rubbing against surfaces ","Dermal - Spray treatment","Dermal - Walking through a hoof disinfection bath","Sum Dermal"]
["Beef cattle"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G6/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$21","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$23*'Defaults 4'!$C$57*'Defaults 4'!$C$58/1000*4*'Defaults 4'!$C$56/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$23","v":0},{"$f":"SUM(C38:E38)","v":0}]
["Dairy cattle"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G7/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$21","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$23*'Defaults 4'!$C$57*'Defaults 4'!$C$58/1000*4*'Defaults 4'!$C$56/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$23","v":0},{"$f":"SUM(C39:E39)","v":0}]
["Calf"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G8/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$21","v":0},null,{"$f":"'Report (Realistic worst case)'!$C$23*'Defaults 4'!$C$57*'Defaults 4'!$C$58/1000*4*'Defaults 4'!$C$56/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$23","v":0},0]
["Fattening pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G9/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Breeding pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!$G$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Breeding pig","individual housing",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!$G$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Breeding pig","group housing",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!$G$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Sheep"," - ",null,null,null,0]
["Lamb"," - ",null,null,null,0]
["Slaughter goat"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G13/'Defaults 1'!B13*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Lactating goat"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G14/'Defaults 1'!B14*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Broilers"," - ",null,null,null,0]
["Broilers","free range, litter floor",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E16-'Defaults 2'!D16)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C16/'Defaults 1'!B15*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Broilers","parent broilers, free range (grating floor)",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E17-'Defaults 2'!D17)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C17/'Defaults 1'!B15*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Broilers","parent broilers in rearing, free range (grating floor)",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E18-'Defaults 2'!D18)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C18/'Defaults 1'!B15*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Laying hen"," - ",null,null,null,0]
["Laying hen","battery",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E19-'Defaults 2'!D19)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C19/'Defaults 1'!B16*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Laying hen","free range (litter floor)",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E20-'Defaults 2'!D20)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C20/'Defaults 1'!B16*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Laying hen","free range (grating floor)",null,{"$f":"'Report (Realistic worst case)'!$C$22*('Defaults 2'!E21-'Defaults 2'!D21)*'Defaults 4'!$C$6*'Defaults 4'!$C$54/'Defaults 2'!C21/'Defaults 1'!B16*'Report (Realistic worst case)'!$E$22","v":0},null,0]
["Turkey"," - ",null,null,null,0]
["Horse"," - ",{"$f":"'Report (Realistic worst case)'!$C$21*'Defaults 1'!G18/'Defaults 1'!B18*'Report (Realistic worst case)'!$E$21","v":0},null,null,0]
["Rabbit"," - ",null,null,null,0]
["Description of Exposure Model/\nAssumptions",null,"Animal rubs on surface treated with the biocidal product. The exposure estimate includes dermal uptake as well as oral intake from grooming","Wall area of poultry housing is treated with the biocidal product in the presence of animals. 50% of the floor area is covered with animals. ","Animals walk through shallow tubs containing a hoof bath as they enter or exit the stable/milking facility. During each pass a layer of 0,01 cm of the biocidal product is in contact with the animal´s skin/hoof. For dairy cattle 3 daily passes, for beef cattle   1 daily pass through the hoof bath are assumed. "]
["Calculation",null,"Exposure\n=AR*BSAcont/bw*RF","Exposure=AR*Awall*EF*Fcovered/Noanim/bw*RF","Exposure=AR*Ahoof*L/1000*Nohoof*Nopass/bw*RF"]
["Parameters/\nDefault Values",null,"AR: application rate (mg/m2)","AR: application rate (mg/m2)","AR: application rate (mg/L)"]
[null,null,"BSAcont: animal body surface area in contact with surface (m2) \n(Defaults 1)","Awall: wall area per stable (m2) (default, Defaults 2)","Ahoof: exposed hoof area (cm²) (default=1590 cm², Defaults 4)"]
[null,null,"bw: body weight (kg)\n(default, Defaults 1)","EF: emission factor for spray application: fraction emitted to floor during surface treatment \n(default=0,11), Defaults 4)","L: thickness of layer of product in contact with skin  or hoof (cm) (default=0,01 cm, Defaults 4)"]
[null,null,"RF: refinement factor\n(default=1)","Fcovered: fraction of floor area covered with hens (default=50%, Defaults 4)","Nohoof: No of hoofs per animal (default =4)"]
[null,null,null,"Noanim: No. of animals per stable \n(default, Defaults 2)","Nopass: No of daily passes through hoof bath (default=2 for dairy cattle (Defaults 4), also applied for beef cattle and calf)"]
[null,null,null,"bw: body weight (kg)\n(Defaults 1)","bw: body weight (kg)\n(Defaults 1)"]
[null,null,null,"RF: refinement factor\n(default=1)","RF: refinement factor\n(default=1)"]
[]
["Inhalation Scenarios"]
["Animal Species",null,"Inhalative - Inhalation after air space treatment","Inhalative - Saturated Vapour Concentration Model (SVC)","Sum Inhalative "]
["Beef cattle"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I6/'Defaults 1'!B6*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I6/'Defaults 1'!B6*'Report (Realistic worst case)'!$F$27","v":0},{"$f":"SUM(C72:D72)","v":0}]
["Dairy cattle"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I7/'Defaults 1'!B7*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I7/'Defaults 1'!B7*'Report (Realistic worst case)'!$F$27","v":0},{"$f":"SUM(C73:D73)","v":0}]
["Calf"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I8/'Defaults 1'!B8*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I8/'Defaults 1'!B8*'Report (Realistic worst case)'!$F$27","v":0},0]
["Fattening pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I9/'Defaults 1'!B9*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I9/'Defaults 1'!B9*'Report (Realistic worst case)'!$F$27","v":0},0]
["Breeding pig"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$F$27","v":0},0]
["Breeding pig","individual housing",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$F$27","v":0},0]
["Breeding pig","group housing",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$10/'Defaults 1'!$B$10*'Report (Realistic worst case)'!$F$27","v":0},0]
["Sheep"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I11/'Defaults 1'!B11*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I11/'Defaults 1'!B11*'Report (Realistic worst case)'!$F$27","v":0},0]
["Lamb"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I12/'Defaults 1'!B12*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I12/'Defaults 1'!B12*'Report (Realistic worst case)'!$F$27","v":0},0]
["Slaughter goat"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I13/'Defaults 1'!B13*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I13/'Defaults 1'!B13*'Report (Realistic worst case)'!$F$27","v":0},0]
["Lactating goat"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I14/'Defaults 1'!B14*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I14/'Defaults 1'!B14*'Report (Realistic worst case)'!$F$27","v":0},0]
["Broilers"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$F$27","v":0},0]
["Broilers","free range, litter floor",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$F$27","v":0},0]
["Broilers","parent broilers, free range (grating floor)",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$F$27","v":0},0]
["Broilers","parent broilers in rearing, free range (grating floor)",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$15/'Defaults 1'!$B$15*'Report (Realistic worst case)'!$F$27","v":0},0]
["Laying hen"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$F$27","v":0},0]
["Laying hen","battery",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$F$27","v":0},0]
["Laying hen","free range (litter floor)",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$F$27","v":0},0]
["Laying hen","free range (grating floor)",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!$I$16/'Defaults 1'!$B$16*'Report (Realistic worst case)'!$F$27","v":0},0]
["Turkey"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I17/'Defaults 1'!B17*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I17/'Defaults 1'!B17*'Report (Realistic worst case)'!$F$27","v":0},0]
["Horse"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I18/'Defaults 1'!B18*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I18/'Defaults 1'!B18*'Report (Realistic worst case)'!$F$27","v":0},0]
["Rabbit"," - ",{"$f":"'Report (Realistic worst case)'!$C$24*'Defaults 1'!I19/'Defaults 1'!B19*'Report (Realistic worst case)'!$E$24","v":0},{"$f":"'Report (Realistic worst case)'!$D$27*'Report (Realistic worst case)'!$C$27/'Defaults 4'!$C$62/'Report (Realistic worst case)'!$E$27*1000*'Defaults 1'!I19/'Defaults 1'!B19*'Report (Realistic worst case)'!$F$27","v":0},0]
["Description of Exposure Model/\nAssumptions",null,"Resting animal is exposed to air containing the a.s. at the specified concentration (to acccount for animal activity multiply result by 3).","Resting animal is exposed to air containing the a.s. at its saturated vapour concentration (SVC) (to acccount for animal activity multiply result by 3)."]
["Calculation",null,"Exposure=Cair *AVR/bw*RF","Exposure=(P*MW/R/T *1000) *AVR/bw*RF"]
["Parameters/\nDefault Values",null,"Cair: air concentration at time of re-entry (mg/m3) ","P: vapour pressure of a.s. (Pa)"]
[null,null,"AVR: alveolar ventilation rate (m³/d) \n(default, Defaults 1)","T: temperature (K)"]
[null,null,"bw: body weight (kg)\n(default, Defaults 1)","MW: molecular weight of a.s. (g/mol)"]
[null,null,"RF: refinement factor\n(default=1)","R: gas constant\n(R=8,31451 J/K*mol)"]
[null,null,null,"AVR: alveolar ventilation rate (m³/d) \n(default, Defaults 1)"]
[null,null,null,"bw: body weight (kg)\n(default, Defaults 1)"]
[null,null,null,"RF: refinement factor\n(default=1)"]

{"sheet":"Calc (WCCE)","index":7,"n_rows":127,"n_cols":10,"rows_kept":127,"cut":false,"hidden":false,"merged":[[3,0,3,6],[17,0,17,5],[55,0,55,13],[90,0,90,5],[91,2,91,3],[91,4,91,5],[18,2,18,3],[18,4,18,5],[86,1,86,6],[59,4,59,9]]}
["Worst Case Consumer Exposure (mg a.s./kg bw/d)"]
[]
[]
["Highest estimated livestock exposure (RWCE) values "]
["Animal group","Animal Species","Housing condition","Sum of \nall routes of exposure","Sum of \nall oral routes of exposure","Sum of \nall dermal routes of exposure","Sum of \nall inhalative routes of exposure"]
["All animals",{"$f":"INDEX('Report (Realistic worst case)'!$A$90:$A$111,MATCH(D6,'Report (Realistic worst case)'!$C$90:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$90:$B$111,MATCH(D6,'Report (Realistic worst case)'!$C$90:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!C90:C111)","v":0},{"$f":"VLOOKUP(B6&C6,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B6&C6,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B6&C6,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Bovine",{"$f":"INDEX('Report (Realistic worst case)'!$A$90:$A$92,MATCH(D7,'Report (Realistic worst case)'!$C$90:$C$92,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$90:$B$92,MATCH(D7,'Report (Realistic worst case)'!$C$90:$C$92,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!C90:C92)","v":0},{"$f":"VLOOKUP(B7&C7,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B7&C7,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B7&C7,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Pig",{"$f":"INDEX('Report (Realistic worst case)'!$A$93:$A$96,MATCH(D8,'Report (Realistic worst case)'!$C$93:$C$96,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$93:$B$96,MATCH(D8,'Report (Realistic worst case)'!$C$93:$C$96,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)","v":0},{"$f":"VLOOKUP(B8&C8,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B8&C8,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B8&C8,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Sheep",{"$f":"INDEX('Report (Realistic worst case)'!$A$97:$A$98,MATCH(D9,'Report (Realistic worst case)'!$C$97:$C$98,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$97:$B$98,MATCH(D9,'Report (Realistic worst case)'!$C$97:$C$98,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)","v":0},{"$f":"VLOOKUP(B9&C9,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B9&C9,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B9&C9,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Goat",{"$f":"INDEX('Report (Realistic worst case)'!$A$99:$A$100,MATCH(D10,'Report (Realistic worst case)'!$C$99:$C$100,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$99:$B$100,MATCH(D10,'Report (Realistic worst case)'!$C$99:$C$100,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$99:$C$100)","v":0},{"$f":"VLOOKUP(B10&C10,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B10&C10,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B10&C10,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Poultry",{"$f":"INDEX('Report (Realistic worst case)'!$A$101:$A$109,MATCH(D11,'Report (Realistic worst case)'!$C$101:$C$109,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$101:$B$109,MATCH(D11,'Report (Realistic worst case)'!$C$101:$C$109,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)","v":0},{"$f":"VLOOKUP(B11&C11,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B11&C11,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B11&C11,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Horse",{"$f":"INDEX('Report (Realistic worst case)'!$A$110:$A$110,MATCH(D12,'Report (Realistic worst case)'!$C$110:$C$110,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$110:$B$110,MATCH(D12,'Report (Realistic worst case)'!$C$110:$C$110,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$110)","v":0},{"$f":"VLOOKUP(B12&C12,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B12&C12,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B12&C12,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Rabbit",{"$f":"INDEX('Report (Realistic worst case)'!$A$111:$A$111,MATCH(D13,'Report (Realistic worst case)'!$C$111:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$111:$B$111,MATCH(D13,'Report (Realistic worst case)'!$C$111:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!$C$111)","v":0},{"$f":"VLOOKUP(B13&C13,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B13&C13,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B13&C13,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Milk producing animals",{"$f":"INDEX('Report (Realistic worst case)'!$A$90:$A$111,MATCH(D14,'Report (Realistic worst case)'!$C$90:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$90:$B$111,MATCH(D14,'Report (Realistic worst case)'!$C$90:$C$111,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!C91,'Report (Realistic worst case)'!C97,'Report (Realistic worst case)'!C100)","v":0},{"$f":"VLOOKUP(B14&C14,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B14&C14,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B14&C14,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Egg producing animals",{"$f":"INDEX('Report (Realistic worst case)'!$A$105:$A$108,MATCH(D15,'Report (Realistic worst case)'!$C$105:$C$108,0))","v":{"$error":"#N/A"}},{"$f":"INDEX('Report (Realistic worst case)'!$B$101:$B$109,MATCH(D15,'Report (Realistic worst case)'!$C$101:$C$109,0))","v":{"$error":"#N/A"}},{"$f":"MAX('Report (Realistic worst case)'!C105:C108)","v":0},{"$f":"VLOOKUP(B15&C15,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$5:$A$26&'Calc (Realistic worst case)'!$B$5:$B$26,'Calc (Realistic worst case)'!$I$5:$I$26),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B15&C15,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$37:$A$59&'Calc (Realistic worst case)'!$B$37:$B$59,'Calc (Realistic worst case)'!$F$37:$F$59),2,0)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(B15&C15,CHOOSE({1,2},'Calc (Realistic worst case)'!$A$72:$A$93&'Calc (Realistic worst case)'!$B$72:$B$93,'Calc (Realistic worst case)'!$E$72:$E$93),2,0)","v":{"$error":"#N/A"}}]
["Please note that some scenarios for chicken and pigs distinguish between several housing conditions. "]
[]
["WCCE using EFSA PRIMo rev 3",null,null,null,null,null,"EMA food basket"]
[null,null,"chronic",null,"acute",null,"chronic"]
[null,null,"adult","child","adult","child","adult"]
["Bovine","all edible tissues (except milk)",{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G10/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J10/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!D10/1000","v":0}]
["Bovine","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G11/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J11/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G53/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J53/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!D11/1000","v":0}]
["Bovine","fat",{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G12/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J12/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G54/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J54/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!D12/1000","v":0}]
["Bovine","liver",{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G13/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J13/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G55/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J55/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!D13/1000","v":0}]
["Bovine","kidney",{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G14/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J14/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!G56/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!J56/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$90,'Report (Realistic worst case)'!$C$92)*'Defaults 5 Food Cons.'!D14/1000","v":0}]
["Bovine","milk",{"$f":"'Report (Realistic worst case)'!C91*'Defaults 5 Food Cons.'!G15/1000","v":0},{"$f":"'Report (Realistic worst case)'!C91*'Defaults 5 Food Cons.'!J15/1000","v":0},{"$f":"'Report (Realistic worst case)'!C91*'Defaults 5 Food Cons.'!G57/1000","v":0},{"$f":"'Report (Realistic worst case)'!C91*'Defaults 5 Food Cons.'!J57/1000","v":0},{"$f":"'Report (Realistic worst case)'!C91*'Defaults 5 Food Cons.'!D15/1000","v":0}]
["Pig","all edible tissues",{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G16/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J16/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!D16/1000","v":0}]
["Pig","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G17/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J17/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G59/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J59/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!D17/1000","v":0}]
["Pig","fat",{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G18/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J18/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G60/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J60/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!D18/1000","v":0}]
["Pig","liver",{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G19/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J19/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G61/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J61/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!D19/1000","v":0}]
["Pig","kidney",{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G20/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J20/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!G62/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!J62/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$93:$C$96)*'Defaults 5 Food Cons.'!D20/1000","v":0}]
["Sheep","all edible tissues (except milk)",{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G21/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!J21/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!D21/1000","v":0}]
["Sheep","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G22/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!J22/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G64/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!J64/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!D22/1000","v":0}]
["Sheep","fat",null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!J23/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!D23/1000","v":0}]
["Sheep","liver",{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G24/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!J24/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G66/1000","v":0},null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!D24/1000","v":0}]
["Sheep","kidney",{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G25/1000","v":0},null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!G67/1000","v":0},null,{"$f":"MAX('Report (Realistic worst case)'!$C$97:$C$98)*'Defaults 5 Food Cons.'!D25/1000","v":0}]
["Sheep","milk",{"$f":"('Report (Realistic worst case)'!$C$97)*'Defaults 5 Food Cons.'!G26/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$97)*'Defaults 5 Food Cons.'!J26/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$97)*'Defaults 5 Food Cons.'!G68/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$97)*'Defaults 5 Food Cons.'!J68/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$97)*'Defaults 5 Food Cons.'!D26/1000","v":0}]
["Goat","all edible tissues (except milk)",{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!G27/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!J27/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!D27/1000","v":0}]
["Goat","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!G28/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!J28/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!G70/1000","v":0},null,{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!D28/1000","v":0}]
["Goat","fat",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!D29/1000","v":0}]
["Goat","liver",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!D30/1000","v":0}]
["Goat","kidney",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$99)*'Defaults 5 Food Cons.'!D31/1000","v":0}]
["Goat","milk",{"$f":"('Report (Realistic worst case)'!$C$100)*'Defaults 5 Food Cons.'!G32/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$100)*'Defaults 5 Food Cons.'!J32/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$100)*'Defaults 5 Food Cons.'!G71/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$100)*'Defaults 5 Food Cons.'!J71/1000","v":0},{"$f":"('Report (Realistic worst case)'!$C$100)*'Defaults 5 Food Cons.'!D32/1000","v":0}]
["Poultry","all edible tissues (except eggs)",{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G33/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J33/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!D33/1000","v":0}]
["Poultry","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G34/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J34/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G73/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J73/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!D34/1000","v":0}]
["Poultry","fat",{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G35/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J35/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G74/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J74/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!D35/1000","v":0}]
["Poultry","liver",{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G36/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J36/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G75/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J75/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!D36/1000","v":0}]
["Poultry","kidney",{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G37/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!J37/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!G76/1000","v":0},null,{"$f":"MAX('Report (Realistic worst case)'!$C$101:$C$109)*'Defaults 5 Food Cons.'!D37/1000","v":0}]
["Poultry","eggs",{"$f":"MAX('Report (Realistic worst case)'!$C$105:$C$108)*'Defaults 5 Food Cons.'!G38/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$105:$C$108)*'Defaults 5 Food Cons.'!J38/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$105:$C$108)*'Defaults 5 Food Cons.'!G77/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$105:$C$108)*'Defaults 5 Food Cons.'!J77/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$105:$C$108)*'Defaults 5 Food Cons.'!D38/1000","v":0}]
["Horse","all edible tissues",{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!G39/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!J39/1000","v":0},null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!D39/1000","v":0}]
["Horse","muscle",{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!G40/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!J40/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!G79/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!J79/1000","v":0},{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!D40/1000","v":0}]
["Horse","fat",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!D41/1000","v":0}]
["Horse","liver",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!D42/1000","v":0}]
["Horse","kidney",null,null,null,null,{"$f":"MAX('Report (Realistic worst case)'!$C$110)*'Defaults 5 Food Cons.'!D43/1000","v":0}]
[]
["Worst Case Consumer Exposure refined with empirical transfer factors  based on the Octanol–Water Partition Coefficient (log P_O/W) [mg/kg bw/d]"]
[]
["Livestock Exposure (mg a.s./kg bw/d)"]
["Only checked scenarios included"]
[null,null,null,null,"Total livestock exposure = Sum Oral * TF based on logPOW + Sum Dermal and Inhalative"]
["Animal Species",null,"Sum Oral Exposure","Sum Dermal and Inhalative Exposure","Eggs","Milk","Muscle","Fat","Liver","Kidney"]
["Beef cattle"," - ",{"$f":"'Calc (Realistic worst case)'!I5","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C38:E38,'Calc (Realistic worst case)'!C72:D72)","v":0},null,null,{"$f":"($C62*D$89)+$D62","v":{"$error":"#N/A"}},{"$f":"($C62*E$89)+$D62","v":{"$error":"#N/A"}},{"$f":"($C62*F$89)+$D62","v":{"$error":"#N/A"}},{"$f":"($C62*G$89)+$D62","v":{"$error":"#N/A"}}]
["Dairy cattle"," - ",{"$f":"'Calc (Realistic worst case)'!I6","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C39:E39,'Calc (Realistic worst case)'!C73:D73)","v":0},null,{"$f":"($C63*C$89)+$D63","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Calf"," - ",{"$f":"'Calc (Realistic worst case)'!I7","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C40:E40,'Calc (Realistic worst case)'!C74:D74)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Fattening pig"," - ",{"$f":"'Calc (Realistic worst case)'!I8","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C41:E41,'Calc (Realistic worst case)'!C75:D75)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Breeding pig"," - ",{"$f":"'Calc (Realistic worst case)'!I9","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C42:E42,'Calc (Realistic worst case)'!C76:D76)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Breeding pig","individual housing",{"$f":"'Calc (Realistic worst case)'!I10","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C43:E43,'Calc (Realistic worst case)'!C77:D77)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Breeding pig","group housing",{"$f":"'Calc (Realistic worst case)'!I11","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C44:E44,'Calc (Realistic worst case)'!C78:D78)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Sheep"," - ",{"$f":"'Calc (Realistic worst case)'!I12","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C45:E45,'Calc (Realistic worst case)'!C79:D79)","v":0},null,{"$f":"($C69*C$89)+$D69","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Lamb"," - ",{"$f":"'Calc (Realistic worst case)'!I13","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C46:E46,'Calc (Realistic worst case)'!C80:D80)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Slaughter goat"," - ",{"$f":"'Calc (Realistic worst case)'!I14","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C47:E47,'Calc (Realistic worst case)'!C81:D81)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Lactating goat"," - ",{"$f":"'Calc (Realistic worst case)'!I15","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C48:E48,'Calc (Realistic worst case)'!C82:D82)","v":0},null,{"$f":"($C72*C$89)+$D72","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Broilers"," - ",{"$f":"'Calc (Realistic worst case)'!I16","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C49:E49,'Calc (Realistic worst case)'!C83:D83)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Broilers","free range, litter floor",{"$f":"'Calc (Realistic worst case)'!I17","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C50:E50,'Calc (Realistic worst case)'!C84:D84)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Broilers","parent broilers, free range (grating floor)",{"$f":"'Calc (Realistic worst case)'!I18","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C51:E51,'Calc (Realistic worst case)'!C85:D85)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Broilers","parent broilers in rearing, free range (grating floor)",{"$f":"'Calc (Realistic worst case)'!I19","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C52:E52,'Calc (Realistic worst case)'!C86:D86)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Laying hen"," - ",{"$f":"'Calc (Realistic worst case)'!I20","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C53:E53,'Calc (Realistic worst case)'!C87:D87)","v":0},{"$f":"($C77*B$89)+$D77","v":{"$error":"#N/A"}},null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Laying hen","battery",{"$f":"'Calc (Realistic worst case)'!I21","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C54:E54,'Calc (Realistic worst case)'!C88:D88)","v":0},{"$f":"($C78*B$89)+$D78","v":{"$error":"#N/A"}},null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Laying hen","free range (litter floor)",{"$f":"'Calc (Realistic worst case)'!I22","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C55:E55,'Calc (Realistic worst case)'!C89:D89)","v":0},{"$f":"($C79*B$89)+$D79","v":{"$error":"#N/A"}},null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Laying hen","free range (grating floor)",{"$f":"'Calc (Realistic worst case)'!I23","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C56:E56,'Calc (Realistic worst case)'!C90:D90)","v":0},{"$f":"($C80*B$89)+$D80","v":{"$error":"#N/A"}},null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Turkey"," - ",{"$f":"'Calc (Realistic worst case)'!I24","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C57:E57,'Calc (Realistic worst case)'!C91:D91)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Horse"," - ",{"$f":"'Calc (Realistic worst case)'!I25","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C58:E58,'Calc (Realistic worst case)'!C92:D92)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Rabbit"," - ",{"$f":"'Calc (Realistic worst case)'!I26","v":0},{"$f":"SUM('Calc (Realistic worst case)'!C59:E59,'Calc (Realistic worst case)'!C93:D93)","v":0},null,null,{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
["Please note that some scenarios for chicken and pigs distinguish between several housing conditions. "]
[]
["Selected LogPOW range:",null,{"$f":"'Report (WCCE)'!C11","v":"< choose a logPOW range >"}]
[null,"Transfer factors"]
["LogPOW","Eggs","Milk","Muscle","Fat","Liver","Kidney"]
[{"$f":"C86","v":"< choose a logPOW range >"},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,2,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,3,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,5,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,6,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP($A$89,'Defaults 6 LogP_OW'!$A$5:$G$14,7,FALSE)","v":{"$error":"#N/A"}}]
[]
["WCCE using EFSA PRIMo rev 3",null,null,null,null,null,"EMA food basket"]
[null,null,"chronic",null,"acute",null,"chronic"]
[null,null,"adult","child","adult","child","adult"]
["Bovine","all edible tissues (except milk)"]
["Bovine","muscle",{"$f":"(($D$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G11/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J11/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G53/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J53/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!D11/1000","v":{"$error":"#N/A"}}]
["Bovine","fat",{"$f":"(($E$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G12/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J12/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G54/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J54/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!D12/1000","v":{"$error":"#N/A"}}]
["Bovine","liver",{"$f":"(($F$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G13/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J13/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G55/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J55/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!D13/1000","v":{"$error":"#N/A"}}]
["Bovine","kidney",{"$f":"(($G$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G14/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J14/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!G56/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!J56/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$7)+($F$7+$G$7))*'Defaults 5 Food Cons.'!D14/1000","v":{"$error":"#N/A"}}]
["Bovine","milk",{"$f":"(($C$89*$C$63)+($D$63))*'Defaults 5 Food Cons.'!G15/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$63)+($D$63))*'Defaults 5 Food Cons.'!J15/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$63)+($D$63))*'Defaults 5 Food Cons.'!G57/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$63)+($D$63))*'Defaults 5 Food Cons.'!J57/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$63)+($D$63))*'Defaults 5 Food Cons.'!D15/1000","v":{"$error":"#N/A"}}]
["Pig","all edible tissues"]
["Pig","muscle",{"$f":"(($D$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G17/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J17/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G59/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J59/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!D17/1000","v":{"$error":"#N/A"}}]
["Pig","fat",{"$f":"(($E$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G18/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J18/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G60/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J60/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!D18/1000","v":{"$error":"#N/A"}}]
["Pig","liver",{"$f":"(($F$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G19/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J19/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G61/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J61/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!D19/1000","v":{"$error":"#N/A"}}]
["Pig","kidney",{"$f":"(($G$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G20/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J20/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!G62/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!J62/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$8)+($F$8+$G$8))*'Defaults 5 Food Cons.'!D20/1000","v":{"$error":"#N/A"}}]
["Sheep","all edible tissues (except milk)"]
["Sheep","muscle",{"$f":"(($D$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G22/1000","v":{"$error":"#N/A"}},{"$f":"((D89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!J22/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G64/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!J64/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!D22/1000","v":{"$error":"#N/A"}}]
["Sheep","fat",null,{"$f":"(($E$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!J23/1000","v":{"$error":"#N/A"}},null,null,{"$f":"(($E$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!D23/1000","v":{"$error":"#N/A"}}]
["Sheep","liver",{"$f":"(($F$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G24/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!J24/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G66/1000","v":{"$error":"#N/A"}},null,{"$f":"(($F$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!D24/1000","v":{"$error":"#N/A"}}]
["Sheep","kidney",{"$f":"((G89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G25/1000","v":{"$error":"#N/A"}},null,{"$f":"(($G$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!G67/1000","v":{"$error":"#N/A"}},null,{"$f":"(($G$89*$E$9)+($F$9+$G$9))*'Defaults 5 Food Cons.'!D25/1000","v":{"$error":"#N/A"}}]
["Sheep","milk",{"$f":"(($C$89*$C$69)+($D$69))*'Defaults 5 Food Cons.'!G26/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$69)+($D$69))*'Defaults 5 Food Cons.'!J26/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$69)+($D$69))*'Defaults 5 Food Cons.'!G68/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$69)+($D$69))*'Defaults 5 Food Cons.'!J68/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$69)+($D$69))*'Defaults 5 Food Cons.'!D26/1000","v":{"$error":"#N/A"}}]
["Goat","all edible tissues (except milk)"]
["Goat","muscle",{"$f":"(($D$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!G28/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!J28/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!G70/1000","v":{"$error":"#N/A"}},null,{"$f":"(($D$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!D28/1000","v":{"$error":"#N/A"}}]
["Goat","fat",null,null,null,null,{"$f":"(($E$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!D29/1000","v":{"$error":"#N/A"}}]
["Goat","liver",null,null,null,null,{"$f":"(($F$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!D30/1000","v":{"$error":"#N/A"}}]
["Goat","kidney",null,null,null,null,{"$f":"(($G$89*$E$10)+($F$10+$G$10))*'Defaults 5 Food Cons.'!D31/1000","v":{"$error":"#N/A"}}]
["Goat","milk",{"$f":"(($C$89*$C$72)+($D$72))*'Defaults 5 Food Cons.'!G32/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$72)+($D$72))*'Defaults 5 Food Cons.'!J32/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$72)+($D$72))*'Defaults 5 Food Cons.'!G71/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*$C$72)+($D$72))*'Defaults 5 Food Cons.'!J71/1000","v":{"$error":"#N/A"}},{"$f":"(($C$89*($C$72))+($D$72))*'Defaults 5 Food Cons.'!D32/1000","v":{"$error":"#N/A"}}]
["Poultry","all edible tissues (except eggs)"]
["Poultry","muscle",{"$f":"(($D$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G34/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J34/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G73/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J73/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!D34/1000","v":{"$error":"#N/A"}}]
["Poultry","fat",{"$f":"(($E$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G35/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J35/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G74/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J74/1000","v":{"$error":"#N/A"}},{"$f":"(($E$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!D35/1000","v":{"$error":"#N/A"}}]
["Poultry","liver",{"$f":"(($F$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G36/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J36/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G75/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J75/1000","v":{"$error":"#N/A"}},{"$f":"(($F$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!D36/1000","v":{"$error":"#N/A"}}]
["Poultry","kidney",{"$f":"(($G$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G37/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!J37/1000","v":{"$error":"#N/A"}},{"$f":"(($G$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!G76/1000","v":{"$error":"#N/A"}},null,{"$f":"(($G$89*$E$11)+($F$11+$G$11))*'Defaults 5 Food Cons.'!D37/1000","v":{"$error":"#N/A"}}]
["Poultry","eggs",{"$f":"(($B$89*$E$15)+($F$15+$G$15))*'Defaults 5 Food Cons.'!G38/1000","v":{"$error":"#N/A"}},{"$f":"(($B$89*$E$15)+($F$15+$G$15))*'Defaults 5 Food Cons.'!J38/1000","v":{"$error":"#N/A"}},{"$f":"(($B$89*$E$15)+($F$15+$G$15))*'Defaults 5 Food Cons.'!G77/1000","v":{"$error":"#N/A"}},{"$f":"(($B$89*$E$15)+($F$15+$G$15))*'Defaults 5 Food Cons.'!J77/1000","v":{"$error":"#N/A"}},{"$f":"(($B$89*$E$15)+($F$15+$G$15))*'Defaults 5 Food Cons.'!D38/1000","v":{"$error":"#N/A"}}]
["Horse","all edible tissues"]
["Horse","muscle",{"$f":"(($D$89*$C$82)+($D$82))*'Defaults 5 Food Cons.'!G40/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$C$82)+($D$82))*'Defaults 5 Food Cons.'!J40/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$C$82)+($D$82))*'Defaults 5 Food Cons.'!G79/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$C$82)+($D$82))*'Defaults 5 Food Cons.'!J79/1000","v":{"$error":"#N/A"}},{"$f":"(($D$89*$E$12)+($F$12+$G$12))*'Defaults 5 Food Cons.'!D40/1000","v":{"$error":"#N/A"}}]
["Horse","fat",null,null,null,null,{"$f":"(($E$89*$E$12)+($F$12+$G$12))*'Defaults 5 Food Cons.'!D41/1000","v":{"$error":"#N/A"}}]
["Horse","liver",null,null,null,null,{"$f":"(($F$89*$E$12)+($F$12+$G$12))*'Defaults 5 Food Cons.'!D42/1000","v":{"$error":"#N/A"}}]
["Horse","kidney",null,null,null,null,{"$f":"(($G$89*$E$12)+($F$12+$G$12))*'Defaults 5 Food Cons.'!D43/1000","v":{"$error":"#N/A"}}]

{"sheet":"Defaults 1","index":8,"n_rows":19,"n_cols":11,"rows_kept":19,"cut":false,"hidden":false,"merged":[[3,2,3,4],[0,0,0,7]]}
["Default Values (1): Animal Size and Physiology (except fish)\n"]
["(Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure, Appendix 6-1, Table 52)"]
[]
["Animal Species","Body weight (kg)","Animal height (cm)",null,null,"Body surface area (m2) ","Body surface area in contact with surface (m2) ","Alveolar ventilation rate (l/h) ","Alveolar ventilation rate (m3/d)","Feed intake (kg/day) ","Drinking water intake (l/d) "]
[null,null,"Height to withers or shoulder","height to top of head","maximum reaching height","calculated from default bw","(30% of total body surface area)","resting AVR calculated from default bw, to account for activity use a correction factor of 3","resting AVR calculated from default bw, to account for activity use a correction factor of 3","based on default bw","based on default bw"]
["Beef cattle",500,145,161,177,4.8,1.44,2110,51,12,50]
["Dairy cattle",650,145,161,177,5.6,1.68,2589,62,25,115]
["Calf",200,116,129,142,2.9,0.87,1032,25,8,20]
["Fattening pig",100,77,"/",92,1.5,0.45,601,14,3,10]
["Breeding pig",260,110,"/",125,2.8,0.84,1267,30,6,15]
["Sheep",75,65,72,79,1.5,0.45,480,12,2.5,10]
["Lamb",40,61,67,73,1,0.3,294,7,1.7,5]
["Slaughter goat",13,43,57,200,0.5,0.15,122,3,0.5,1.3]
["Lactating goat",70,76,100,200,1.5,0.45,455,11,2.8,7]
["Broilers",1.7,"/",25,"/",0.05,1.4999999999999999E-2,8.1999999999999993,0.2,0.12,0.25]
["Laying hen",1.9,"/",25,"/",0.05,1.4999999999999999E-2,8.9,0.2,0.13,0.25]
["Turkey",7,"/",34,"/",0.3,0.09,23,0.6,0.5,1]
["Horse",400,158,196,234,5.4,1.62,1773,43,16,40]
["Rabbit",2.5,"/",30,"/",0.2,0.06,34,0.9,0.25,0.5]

{"sheet":"Defaults 2","index":9,"n_rows":30,"n_cols":19,"rows_kept":30,"cut":false,"hidden":false,"merged":[[3,7,3,8],[3,9,3,10],[3,13,3,14],[3,15,3,16],[3,17,3,18],[3,11,3,12]]}
["Default Values (2):  Animal housing"]
["(Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure, Appendix 6-1, Table 53)"]
[]
["Animal Species","Housing type","Number of animals per stable","Floor area per stable (m2)","Wall and floor area per stable (m2)","Housing volume per stable (m3)","Floor area per animal (m2)","Maximum area (wall) within reach of animal (m2) ",null,"Maximum area within reach of animal (wall+floor) (m2) ",null,"Exposed feed surface (m2)",null,"Ventilation rate housing (m³/h)\nper 500 kg live weight",null,"Ventilation rate housing (m³/h)\nper animal",null,"Ventilation rate housing (1/h)\nair exchanges per hour "]
[null,null,"for rabbits per cage","for rabbits per cage","for rabbits per cage","for rabbits per cage",null,"considering max reaching height","No of compartmentwalls considered","considering max reaching height","No of compartmentwalls considered","in case of direct treatment of troughs","in case of treatment of surfaces surrounding troughs","Winter min","Summer max ","Winter min","Summer max ","Winter min","Summer max "]
["Beef cattle",null,125,370,1000,3063,2.96,10.8,3,13.7,3,2.6,0.7,50,333,50,333,2,13.6]
["Dairy cattle",null,100,1170,1670,9630,11.7,21.4,3,33.1,3,6.6,2.9,67,417,87,542,0.9,5.6]
["Calf",null,80,160,330,590,2,8.5,4,10.5,4,2,0.5,75,500,30,200,4.0999999999999996,27.1]
["Fattening pig",null,400,600,970,2110,1.5,4,3,5.5,3,1.2,0.4,50,500,10,100,1.9,19]
["Breeding pig","individual housing",132,560,910,1960,4.2,9.1,3,13.4,3,2.4,1.1000000000000001,100,1000,52,520,3.5,35]
["Breeding pig","group housing",132,710,1160,2480,5.4,10.3,3,15.7,3,2.8,1.3,100,1000,52,520,2.8,27.7]
["Sheep*"]
["Lamb*"]
["Slaughter goat*"]
["Lactating goat*"]
["Broilers","free range, litter floor",20000,1110,1600,4170,5.6000000000000001E-2,null,null,null,null,null,null,278,1853,0.9,6.3,4.3,30.2]
["Broilers","parent broilers, free range (grating floor)",7000,390,600,1458,5.6000000000000001E-2,null,null,null,null,null,null,278,1853,0.9,6.3,4.3,30.2]
["Broilers","parent broilers in rearing, free range (grating floor)",9000,500,750,1880,5.6000000000000001E-2,null,null,null,null,null,null,278,1853,0.9,6.3,4.3,30.2]
["Laying hen","battery",21000,750,1100,2810,3.5999999999999997E-2,null,null,null,null,null,0.01,175,2000,0.7,7.6,5.2,56.8]
["Laying hen","free range (litter floor)",10000,1430,2030,5360,0.14000000000000001,null,null,null,null,null,null,175,2000,0.7,7.6,1.3,14.2]
["Laying hen","free range (grating floor)",20000,1270,1822,4780,6.4000000000000001E-2,null,null,null,null,null,null,175,2000,0.7,7.6,2.9,31.8]
["Turkey*"]
["Horse*"]
["Rabbit",null,5,0.24,0.84,7.1999999999999995E-2,4.8000000000000001E-2,0.27,4,0.32,4]
[" *No EU documents on housing of sheep, goat, turkey, horse found so far. "]
[]
[]
[]
[]
[null,null,null,null,null,null,null,null,null,null,null,null," "]

{"sheet":"Defaults 3","index":10,"n_rows":20,"n_cols":14,"rows_kept":20,"cut":false,"hidden":false,"merged":[[3,1,3,3],[3,4,3,6],[3,7,3,9],[5,13,18,13]]}
["Default Values (3):  Animal transport"]
["(Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure, Appendix 6-1, Table 54)"]
[]
["Animal Species","Time spent in transport vehicles (h)",null,null,"Truck\n(Default truck of 7.0m x 2.5 m)",null,null,"Compartment",null,null,"Required floor area per animal during transport (m2)","Available wall+floor area per animal (m2) ","Available volume per animal (m3)","Ventilation rate "]
[null,"transport","resting period ","transport","No of floors","No of compartments per floor","No of animals per compartment","Length (m)","Width (m)","relevant height (m)",null,"within a compartment","within a truck of 7.0m x 2.5 m","\n"]
["Beef cattle",14,1,14,1,2,6,3.5,2.5,1.8,1.35,5.0999999999999996,2.6,"Forced ventilation systems\n\n60 m3/h/kN loading capacity (with 1000 kg = 9.80665 kN) and a temperature between 5-30°C"]
["Dairy cattle",14,1,14,1,2,5,3.5,2.5,1.8,1.61,6.1,3.2]
["Calf",14,1,14,2,2,11,3.5,2.5,1.5,0.73,2.4,1.2]
["Fattening pig",24,null,null,3,2,20,3.5,2.5,1,0.43,1,0.4]
["Breeding pig",24,null,null,2,2,10,3.5,2.5,1.3,0.8,2.4,1.1000000000000001]
["Sheep (with wool)",14,1,14,2,2,18,3.5,2.5,0.8,0.47,1,0.4]
["Lamb",9,1,9,3,2,35,3.5,2.5,0.8,0.25,0.5,0.2]
["Slaughter goat",9,1,9,3,2,62,3.5,2.5,1,0.14000000000000001,0.3,0.1]
["Lactating goat",14,1,14,2,2,16,3.5,2.5,1.5,0.53,1.7,0.8]
["Broilers",24,null,null,8,12,53,1.17,1.25,0.27,2.7199999999999998E-2,5.1999999999999998E-2,7.4000000000000003E-3]
["Laying hen",24,null,null,7,40,14,0.88,0.5,0.27,3.04E-2,8.5000000000000006E-2,8.3999999999999995E-3]
["Turkey",24,null,null,6,6,39,1.17,2.5,0.4,7.3499999999999996E-2,0.15,0.03]
["Horse",24,null,null,1,2,5,3.5,2.5,2.4,1.75,7.5,4.2]
["Rabbit*",7,0,null,null,null,14,1.1000000000000001,0.6,0.3,0.05,0.12,1.4E-2]
["* Information for rabbits not specified in the finalised guidance (only reference is given: EFSA AHAW document: \n\nScientific Opinion Concerning the Welfare of Animals during Transport, 12 January 2011\nhttp://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.1966/abstract)"]

{"sheet":"Defaults 4","index":11,"n_rows":63,"n_cols":4,"rows_kept":63,"cut":false,"hidden":false,"merged":[]}
["Default Values (4):  Miscellaneous values"]
["(Guidance on the Biocidal Products Regulation, Vol III Parts B+C, Section 6: Guidance on estimating livestock exposure, Appendix 6-1, Table 55)"]
[]
["Animal Species\n(if relevant for exposure scenario)","Description","Default","Background Information \nRemarks"]
["/","emission factor for spraying (fraction emitted to the treated surface during surface treatment by spraying)",0.85,"Table 55, line 18"]
["/","emission factor for spraying (fraction emitted to floor during surface treatment by spraying)",0.11,"Table 55, line 18"]
["/","emission factor for spraying (fraction emitted to floor during air space treatment by spraying)",0.96,"Table 55, line 18"]
["/","migration rate of a.s. into feed (%)",100,"Table 55, line 25"]
["/","feed silo #1: volume (m3)",13.56,"Table 55, line 24"]
["/","feed silo #1: diameter (m)",2.5499999999999998,"Table 55, line 24"]
["/","feed silo #1: height (m)",4.3,"Table 55, line 24"]
["/","feed silo #1: holding capacity (t)",5.7,"Table 55, line 24"]
["/","feed silo #1: surface (m2)",44.66,"calculated from silo diameter and height"]
["/","feed silo #2: volume (m3)",26.62,"Table 55, line 24"]
["/","feed silo #2: diameter (m)",2.5499999999999998,"Table 55, line 24"]
["/","feed silo #2: height (m)",7.8,"Table 55, line 24"]
["/","feed silo #2: holding capacity (t)",16,"Table 55, line 24"]
["/","feed silo #2: surface (m2)",72.7,"calculated from silo diameter and height"]
["/","feed silo #3: volume (m3)",18,"Table 55, line 24"]
["/","feed silo #3: diameter (m)",2.2999999999999998,"Table 55, line 24"]
["/","feed silo #3: height (m)",6.95,"Table 55, line 24"]
["/","feed silo #3: holding capacity (t)",10.8,"Table 55, line 24"]
["/","feed silo #3: surface (m2)",58.53,"calculated from silo diameter and height"]
["/","feed silo #4: volume (m3)",7.3,"Table 55, line 24"]
["/","feed silo #4: diameter (m)",2,"Table 55, line 24"]
["/","feed silo #4: height (m)",4.8499999999999996,"Table 55, line 24"]
["/","feed silo #4: holding capacity (t)",8.3000000000000007,"Table 55, line 24"]
["/","feed silo #4: surface (m2)",36.76,"calculated from silo diameter and height"]
["/","Slimicides: loss of a.s. with waste water during paper production",0.9,"Table 55, line 26"]
["/","daily paper mill waste water (m3/day)",5000,"Table 55, line 27"]
["/","daily paper production per mill (kg/d)",200000,"Table 55, line 29"]
["/","dry paper weight (mg/cm2)",60,"Table 55, line 30"]
["/","packaging surface in contact with 1 kg feed (cm2)",600,"Table 55, line 31"]
["/","fraction of feed that was packaged in treated cardboard/paper consumed by animals",0.1,"Table 55, line 32"]
["Dairy cattle","milkings per day",2,"Table 55, line 1\nNumber of milkings per day may be more frequent and should be considered accordingly"]
["Dairy cattle","Teat dip (dipping product): volume applied per milking (ml/cow/milking)",10,"Table 55, line 2\nvolume for all 4 teats"]
["Dairy cattle","Teat dip (spraying product): volume applied per milking (ml/cow/milking)",20,"Table 55, line 2\nvolume for all 4 teats"]
["Dairy cattle","Teat dip (foam product): volume applied per milking (ml/cow/milking)","´2-2,5","Table 55, line 2\nvolume for all 4 teats"]
["Cattle","number of ear tags/animal",2,"Table 55, line 7"]
["Chicken","average body weight of fly (mg)","`10-12","Table 55, line 11"]
["Chicken","consumption of sucrose by flies (mg per fly per day)","`2,5-3,5","Table 55, line 11"]
["Chicken","number of dead insects consumed by chicken per day",10,"Table 55, line 10"]
["Calf, pig","surface area of tongue (m2)",8.0000000000000002E-3,"Table 55, line 3 (calf), line 8 (pig)"]
["Calf, pig","number of licks per day",10,"Table 55, line 4 (calf), line 9 (pig)"]
["/","maximum absorption of bp into treated wood by vacuum pressure treatment (L/m3)",50,"Table 55, line 15\namount in outer 1 cm layer of wood"]
["/","maximum absorption of bp into treated wood by dipping (L/m2)",0.05,"Table 55, line 15\namount in outer 1 cm layer of wood"]
["/","wood density (g/cm3)",0.4,"Table 55, line 16"]
["/","thickness of layer \"representing one square meter (m)",5.0000000000000002E-5,"Table 55, line 17"]
["Horse","wood consumption (m3)",1.857E-5,"Table 55, line 13\none reference, no default set"]
["Horse","wood consumption (kg)",0.5,"Table 55, line 13\none reference, no default set"]
["Goat",null,"no information","Table 55, line 13"]
["Rabbit","wood consumption (g)",1.25,"Table 55, line 13\n<0,5% of total feed intake"]
["/","extraction from wood",1,"Table 55, line 14"]
["Chicken","floor area covered by animals",0.5,"Table 55, line 12"]
["Cattle","volume of tub for hoof disinfection (L)",325,"Table 55, line 5"]
["Dairy cattle","daily passes through tub",2,"Table 55, line 6"]
["Dairy cow","exposed skin/hoof area (cm2)",1590,"Table 55, line 22"]
["/","layer of product absorbed on skin or hoof (cm) thickness of layer of product in contact with skin (dermal exposure)",0.01,"Table 55, line 23"]
["/","dislodgable residue",1,"Table 55, line 19"]
["/","inhalable or respirable fraction of product ",1,"Table 55, line 20"]
["/","Ambient temperature (K)",298,"Table 55, line 21, \n298 K = 25°C"]
["/","gas constant (J/K*mol)",8.3145100000000003,"Table 55, line 21"]
["Dairy cattle","daily milk yield (L)",20,"Missing in Table 55, but see page 357"]

{"sheet":"Defaults 5 Food Cons.","index":12,"n_rows":81,"n_cols":10,"rows_kept":81,"cut":false,"hidden":false,"merged":[[5,2,5,3],[5,4,5,9],[47,2,47,3],[47,4,47,9]]}
["Default Values (5):  Food consumption data (chronic and acute)"]
["Regulation (EU) 2018/782. Annex II. Derivation of numerical MRLs  (with regard to Regulation (EC) No 470/2009) "]
["EFSA, 2018. Guidance document on the use of the EFSA Pesticide Residue Intake Model (EFSA PRIMo revision 3.1). "]
[]
["Food consumption data (chronic)"]
["Consumer intake model",null,"EMA Food basket*\n(max. daily intake)",null,"EFSA PRIMo rev 3.1\n(max. daily intake)"]
["Consumer group",null,"adult",null,"adults\nconsumer group with highest mean consumption",null,null,"children\nconsumer group with highest mean consumption"]
["Consumer bw (kg)",null,60,"/",null,"bw (kg) see column below",null,null,"bw (kg) see column below"]
[null,null,"g per person \nper day","g/kg bw/d",null,null,"g/kg bw/d\n",null,null,"g/kg bw/d\n"]
["Bovine","all edible tissues (except milk)",500,{"$f":"C10/C8","v":8.3333333333333339},"SE general",60,4.4000000000000004,"UK infant",8.6999999999999993,1.5286999999999999]
[null,"muscle",300,{"$f":"C11/C8","v":5},"SE general",60,4.4000000000000004,"FR  child 3-15 yrs",18.899999999999999,1.4958]
[null,"fat",50,{"$f":"C12/C8","v":0.83333333333333337},"DK adult",75.099999999999994,6.6600000000000006E-2,"UK toddler",14.6,0.1164]
[null,"liver",100,{"$f":"C13/C8","v":1.6666666666666667},"NL general",65.8,0.02,"NL toddler",10.199999999999999,0.14199999999999999]
[null,"kidney",50,{"$f":"C14/C8","v":0.83333333333333337},"UK adult",76,2.5999999999999999E-3,"UK infant",8.6999999999999993,2.3E-2]
[null,"milk",1500,{"$f":"C15/C8","v":25},"DE women 14-50yr ",67.5,12.386799999999999,"NL toddler",10.199999999999999,59.73]
["Pig","all edible tissues",500,8.3333333333333339,"DE general",76.400000000000006,1.2279,"DK child",21.8,2.3317999999999999]
[null,"muscle",300,5,"RO general",60,1.1499999999999999,"DK child",21.8,2.2273000000000001]
[null,"fat",50,0.83333333333333337,"DK adult",75.099999999999994,0.19969999999999999,"IE child",20,0.1336]
[null,"liver",100,1.6666666666666667,"DK adult",75.099999999999994,3.9899999999999998E-2,"NL toddler",10.199999999999999,0.17599999999999999]
[null,"kidney",50,0.83333333333333337,"FR adult",66.400000000000006,1.2999999999999999E-3,"FR child 3-15 yrs",18.899999999999999,2.8E-3]
["Sheep","all edible tissues (except milk)",500,8.3333333333333339,"IE adult",75.2,0.70079787234042534,"ES child",34.479999999999997,0.1792]
[null,"muscle",300,5,"IE adult",75.2,0.368351063829787,"ES child",34.479999999999997,0.17899999999999999]
[null,"fat",50,0.83333333333333337,null,null,"no data","IE child",20,9.9899399999999992E-3]
[null,"liver",100,1.6666666666666667,"IE adult",75.2,0.22606382978723402,"FR infant",9.1,6.6251596424010198E-3]
[null,"kidney",50,0.83333333333333337,"FR adult",66.400000000000006,1.4537701104865299E-4,null,null,"no data"]
[null,"milk",1500,25,"DE women 14-50 yrs",67.47,0.1468850752196684,"DE child",16.2,0.01]
["Goat","all edible tissues (except milk)",500,8.3333333333333339,"ES adult",68.48,5.1000000000000004E-3,"ES child",34.479999999999997,2.0999999999999999E-3]
[null,"muscle",300,5,"ES adult",68.48,5.1000000000000004E-3,"ES child",34.479999999999997,2.0999999999999999E-3]
[null,"fat",50,0.83333333333333337,null,null,"no data",null,null,"no data"]
[null,"liver",100,1.6666666666666667,null,null,"no data",null,null,"no data"]
[null,"kidney",50,0.83333333333333337,null,null,"no data",null,null,"no data"]
[null,"milk",1500,25,"FR adult",66.400000000000006,9.4498291916019522E-2,"FR toddler 2-3 yrs",13.6,0.35694899845896899]
["Poultry","all edible tissues (except eggs)",500,{"$f":"C33/C8","v":8.3333333333333339},"RO general",60,0.7833,"ES child",34.5,1.2855000000000001]
[null,"muscle",300,{"$f":"C34/C8","v":5},"RO general",60,0.7833,"ES child",34.5,1.2855000000000001]
[null,"fat",90,{"$f":"C35/C8","v":1.5},"FR adult",66.400000000000006,2.0999999999999999E-3,"IE child",20,4.0599999999999997E-2]
[null,"liver",100,{"$f":"C36/C8","v":1.6666666666666667},"FR adult",66.400000000000006,1.0500000000000001E-2,"FR toddler",13.6,4.0300000000000002E-2]
[null,"kidney",10,{"$f":"C37/C8","v":0.16666666666666666},"FR adult",66.400000000000006,2.7000000000000001E-3,"FR child 3-15 yrs",18.899999999999999,1.5E-3]
[null,"eggs",100,{"$f":"C38/C8","v":1.6666666666666667},"SE general",60,0.88329999999999997,"UK infant",8.6999999999999993,1.3448]
["Horse","all edible tissues",500,8.3333333333333339,"NL general",65.8,2.5000000000000001E-2,"NL child",18.399999999999999,8.3000000000000004E-2]
["(Equine)","muscle",300,5,"NL general",65.8,2.5000000000000001E-2,"NL child",18.399999999999999,8.3000000000000004E-2]
[null,"fat",50,0.83333333333333337,null,null,"no data",null,null,"no data"]
[null,"liver",100,1.6666666666666667,null,null,"no data",null,null,"no data"]
[null,"kidney",50,0.83333333333333337,null,null,"no data",null,null,"no data"]
["FISH","muscle and skin in natural proportions",300,{"$f":"C44/C8","v":5},"DE general",76.400000000000006,0.39050000000000001,"FR child 3-15 yrs",18.899999999999999,0.69589999999999996]
["Bees","honey",20,{"$f":"C45/C8","v":0.33333333333333331},"DE general",76.400000000000006,4.1300000000000003E-2,"DE child",16.2,0.1]
[]
["Food consumption data (acute)"]
["Consumer intake model",null,"EMA Food basket*\n(max. daily intake)",null,"EFSA PRIMo rev 3.1\n(max. daily intake)"]
["Consumer group",null,"adult",null,"adults\nconsumer group with highest  consumption",null,null,"children\nconsumer group with highest consumption"]
["Consumer bw (kg)",null,60,"/",null,"bw (kg) see column below",null,null,"bw (kg) see column below"]
["Food consumption",null,"g per person \nper day","g/kg bw/d",null,null,"g/kg bw/d\n",null,null,"g/kg bw/d\n"]
["Bovine","all edible tissues (except milk)"]
[null,"muscle",null,null,"UK 15-18 yrs",63.8,5.7,"DE child",16.149999999999999,7.21]
[null,"fat",null,null,"NL general",65.8,0.97,"UK infant",8.6999999999999993,2.08]
[null,"liver",null,null,"DE general",76.38,4,"UK infant",8.6999999999999993,8.07]
[null,"kidney",null,null,"UK 15-18 yrs",63.8,2.11,"UK toddler",14.5,3.77]
[null,"milk",null,null,"NL general",65.8,38.56,"UK infant",8.6999999999999993,124.22]
["Pig","all edible tissues"]
[null,"muscle",null,null,"NL general",65.8,4.8360000000000003,"CZ 4-6 yrs",21.4,12.11]
[null,"fat",null,null,"FR adult",66.400000000000006,2.0299999999999998,"FR 11-14 yrs",46.3,1.7]
[null,"liver",null,null,"NL general",65.8,1.41,"NL toddler",10.199999999999999,1.23]
[null,"kidney",null,null,"DE woman 14-50 yrs",67.47,2.2000000000000002,"ES child",38.479999999999997,1.27]
["Sheep","all edible tissues (except milk)"]
[null,"muscle",null,null,"NL general ",65.8,4.7350000000000003,"NL child",18.399999999999999,5.4349999999999996]
[null,"fat",null,null,null,null,"no data",null,null,"no data"]
[null,"liver",null,null,"DE women 14-50 yrs",67.47,2.8,null,null,"no data"]
[null,"kidney",null,null,"DE general",76.38,0.1,null,null,"no data"]
[null,"milk",null,null,"DE woman 14-50 yrs",67.47,15.1,"NL child",18.399999999999999,3.5706521739130439]
["Goat","all edible tissues (except milk)"]
[null,"muscle",null,null,"ES adult",68.48,1.5615000000000001,null,null,"no data"]
[null,"milk",null,null,"DE women 14-50 yrs",67.47,18.399999999999999,"ES child",34.479999999999997,24.174600000000002]
["Poultry","all edible tissues (except eggs)"]
[null,"muscle",null,null,"UK vegetarian",66.7,11.75,"CZ 4-6 yrs",21.4,16.989999999999998]
[null,"fat",null,null,"DE general",76.38,0.3,"FR 11-14 yrs",46.3,0.1]
[null,"liver",null,null,"DE general",76.38,4.7,"FR 11-14 yrs",46.3,1.1000000000000001]
[null,"kidney",null,null,"FR adult",66.400000000000006,1.29,null,null,"no data"]
[null,"eggs",null,null,"FR adult",66.400000000000006,4.25,"UK infant",8.6999999999999993,12.41]
["Horse","all edible tissues"]
["(Equine)","muscle",null,null,"DE general population",76.38,4.8,"ES child",34.479999999999997,6.0145999999999997]
["FISH","muscle and skin in natural proportions",null,null,"DE general",76.37,7.9,"UK infant",8.6999999999999993,8.85]
["Bees","honey",null,null,"CZ males 15-17 yrs",65.599999999999994,1.38,"NL toddler",10.199999999999999,3.58]

{"sheet":"Defaults 6 LogP_OW","index":13,"n_rows":17,"n_cols":7,"rows_kept":17,"cut":false,"hidden":false,"merged":[]}
["Default Values (6):  Transfer factor based on the octanol–water partition coefficient (LogPOW)"]
["W. R. Leeman, K. J. Van Den Berg & G. F. Houben (2007) Transfer of chemicals from feed to animal products: The use of transfer factors in risk assessment, Food Additives & Contaminants, 24:1, 1-13, DOI: 10.1080/02652030600815512"]
[]
["LogPOW","Eggs","Milk","Muscle","Fat","Liver","Kidney"]
["<0",0.03,0.02,0.02,0.01,0.02,0.02]
["0–1",0.05,0.03,0.04,0.01,0.3,0.3]
["1–2",0.04,0.02,0.01,0.01,0.02,0.02]
["2–3",0.13,0.01,0.02,0.02,0.04,0.04]
["3–4",0.92,0.33,0.01,14.1,0.21,0.21]
["4–5",0.11,0.03,0.05,0.57999999999999996,0.08,0.08]
["5–6",2.4300000000000002,0.43,0.03,17,1.5,1.5]
["6–7",1.6,0.52,0.33,30,2.62,2.62]
["7–8",0.75,0.9,0.33,16.3,2.79,2.79]
[">8",0.21,0.32,0.04,0.74,0.08,0.08]
["Metals total",0.17,0.12,0.82,0.35,6.61,6.61]
["Accumulating metals",0.17,0.15,1.47,0.74,9.6199999999999992,9.6199999999999992]
["Non-accumulating metals",0,0.06,0.3,0.11,0.72,0.72]

{"sheet":"Refinement Notes Inhalation ","index":14,"n_rows":20,"n_cols":3,"rows_kept":20,"cut":false,"hidden":false,"merged":[[1,0,1,8]]}
["Refinement of inhalation exposure estimate for livestock animals using ConsExpo Web "]
["According to the Guidance on estimating livestock exposure (1) in tier 1 inhalation exposure of livestock animals is estimated using the SVC model, which assumes as worst case that livestock animals are exposed to air containing the active substance at its saturated vapor concentration (SVC). For biocide applications in animal housing this usually results in an overestimation of livestock inhalative exposure. \n\nAs tier 2 the estimation of inhalation exposure may be refined considering more realistic conditions in animal housing such as the amount of biocidal product applied, room volume and room ventilation rates. As an option inhalation exposure may be refined using the ConsExpo Web modelling tool (3) together with livestock specific data as provided in the Guidance on estimating livestock exposure (1). \n\nIn the table below information is given on the input data necessary to perform inhalation exposure estimates in ConsExpo. "]
["Parameter","Remarks","Reference"]
["ConsExpo models","Inhalation: Exposure to vapour \n– constant rate\n– evaporation release mode","ConsExpo Web, Consumer Exposure models, model documentation, Update for ConsExpo Web 1.0.2, section 4.1.1, p. 31 (3)\nhttps://www.rivm.nl/bibliotheek/rapporten/2017-0197.pdf"]
["vapour pressure and related temperature","substance specific value","active substance CAR"]
["molecular weight","substance specific value","active substance CAR"]
["weight fraction substance","fraction of active substance in biocidal product","information on biocidal product"]
["product amount","the amount of total product used in one event (i.e. total amount of biocidal product applied in the animal stable)\n(intended use specific value calculated from worst case application rate and treated area for individual animal species )","biocidal use specific information\nand treated area acc to Guidance on BPR: Volume III Parts B+C, Version 4.0, December 2017 (1)\n"]
["animal body weight","body weight of exposed animal or human,\nspecies specific default values","Guidance on BPR: Volume III Parts B+C, Version 4.0, December 2017 (1) "]
["alveolar ventilation rate / inhalation rate","species specific default values,\ncoose unit as applied in ConsExpo calculation (L/h)","Guidance on BPR: Volume III Parts B+C, Version 4.0, December 2017 81)"]
["absorption fraction / uptake fraction","The fraction of the inhaled compound that enters the blood through the lung wall. The value for this parameter can be obtained from experiments. If no information is available, the value should be set to 1 as worst case.","ConsExpo Web, Consumer Exposure models, model documentation, Update for ConsExpo Web 1.0.2, section 4.1.4, p. 46 (3)"]
["room volume","Volume of the room in which the exposure occurs \n(species specific default values for animal housing)","Guidance on BPR: Volume III Parts B+C, Version 4.0, December 2017 (1) "]
["room ventilation rate","Number of total air changes in the room per time. For example, if it takes 20 minutes for all the air in the room to be exchanged with outdoor air, the ventilation rate is 3 times per hour. \n\nconsider winter season (lower ventilation) as worst case ","Guidance on BPR: Volume III Parts B+C, Version 4.0, December 2017"]
["exposure duration","The total time the exposed person (or animal) is in the room where the chemical is being released.\n\n(default assumption: livestock animals are exposed for 24 h)","biocidal use specific information"]
["emission duration ","A reasonable estimate of the time during which the compound is released\n\n(e.g. assumption: 4 weeks as worst case estimate for time period during which the product is emitted in the stable)","ConsExpo Web, Consumer Exposure models, model documentation, Update for ConsExpo Web 1.0.2, section 4.1.1.3, p. 33 (3)"]
["application duration ","time period during which the product is applied ","biocidal use specific information\n\nConsExpo Web, Consumer Exposure models, model documentation, Update for ConsExpo Web 1.0.2, section 4.1.1.4, p. 35 (3)"]
["(assumed) release area","surface area from which the compound is released\ndepends on intended use","biocidal use specific information"]
["exposure frequency","number of days (per year) on which biocidal product is used (i.e. on which exposure occurs)","biocidal use specific information\n\nfor explanation see ConsExpo Pest Control Fact Sheet (2006; p. 54) (3)"]
["molecular weight of the matrix","calculated value depends on product composition\n\nNeeds to be defined if the compound of interest is not in its pure form, but part of a product. It is the average molecular weight of the rest of the total product (the product minus the compound of interest). It is calculated\nas:\nM_matrix = ∑ j≠i (M_j ×〖wf_j)\nwhere the summation index j is over all compounds in the mixture except for the compound of interest (ith component). \n","ConsExpo Web, Consumer Exposure models, model documentation, Update for ConsExpo Web 1.0.2, section 4.1.1.4, p. 36 (3)"]
[" \nmass transfer rate / coefficient\n","the velocity by which a compound is transferred between the product\nand the air \n\ndefault: 10 m/h\n\n(approach as previously used in ConsExpo 4.1:\nConsExpo offers two models to approximate this rate. \n(1) Langmuir’s method: assumes that diffusion of the compound is infinitely fast and It will as a rule highly overestimate the evaporation rate and predict higher peak concentrations than the more conservative Thibodeaux approximation.\n(2) Thibodeaux’s method: simple approximation of the more elaborate Liss-Slater two layer model describing the evaporation of a substance from water.)","Overarching issues –ConsExpo Web and fact sheets (section 3.2, p. 8) (3)"]