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Department Experimental Toxicology and ZEBET

Since the entry into force of the third amendment of the Animal Welfare Act (TierSchG; 7th August 2013; Federal Gazette I No. 36, P. 2182) and of the regulation implementing the Directive 2010/63/EU (TierSchVersV; 1st August 2013; Fed. Gaz. I No. 47, P. 3125), the BfR with the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) fulfils the following new tasks:

  1. Publication of the non-technical project summaries in accordance with § 8 (6) TierSchG and § 41 TierSchVersV;
  2. Advising the responsible authorities and animal welfare bodies in matters related to the acquisition, breeding, accommodation, care and use of animals in procedures in line with § 15a TierSchG and § 45 TierSchVersV;
  3. Advising the responsible authorities in matters related to alternatives to animal experiments in accordance with § 46 TierSchVersV;
  4. Cooperation with the responsible authorities of other member states and the European Commission on issues concerning the regulatory relevance and suitability of the alternative methods recommended for validation in line with § 16g (2) TierSchG.

To ensure that these tasks are carried out and improve its scientific tasks in political consulting, ZEBET develops and validates new alternative methods and assessment strategies in line with the 3R principle with the goal of replacing or at least reducing animal experiments not only in the authorisation process but also in basic research.

Within the scope of the 3R concept, refinement shall be promoted. Therefore, animal welfare and laboratory animal science are other areas of main interest within the department. In addition, the department is reporting about alternative methods to animal experiments in toxicology and basic research.

The department also represents Germany within the scope of international agreements and programmes on health topics and chemicals safety. Thus, the research field of the department covers a variety of different toxicodynamic and -kinetic aspects relevant for risk assessment.

Through the establishment of a joint professorship between the BfR and Charité-Universitätsmedizin Berlin, the 3R principle is spread within academia and is implemented in basic research. Moreover, research on alternative methods to animal experiments is intensified with focus on experimental toxicology.

The department "Experimental Toxicology and ZEBET" is subdivided into five units:

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Contact

Visitors' address
Alt-Marienfelde 17-21
D - 12277 Berlin

Postal address
Postfach 12 69 42
D - 10609 Berlin

Tel.
+49-30-18412-2286

Fax
+49-30-18412-1734

Email
9@bfr.bund.de

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