DevTox project: Harmonized evaluation of anomalies in developmental toxicity studies
The DevTox project comprises the development of a lexicon and a data base as an electronic resource to support the assessment of developmental toxicity studies with regard to the human health risk assessment procedure of plant protection products, biocides, other chemicals and chemical products.
The lexicon is based on a harmonized nomenclature, which was proposed by the International Federation of Teratological Societies (IFTS) and a classification system for external, visceral and skeletal anomalies in common laboratory animals, which was agreed on in several international workshops. The lexicon is connected to date with more than 1000 images, and more images will be continously added during the course of the project. A data base with historical control data ist under development and will be published using this web-site.
The project was initiated by the BfR (formerly BgVV) and is sponsored by the German Federal Ministry of the Environment, Nature Conservation and Nuclear Safety under the auspices of the International Programme of Chemical Safety (IPCS), which is part of the World Health Organisation (WHO). DevTox is developed in collaboration with the Department of Toxicology in the Institute of Clinical Pharmacology and Toxicology at the FU-Berlin and the Fraunhofer Institute of Toxicology and Experimental Medicine in Hannover.
DevTox already provides a valuable resource for health professionals and researchers working in the field of developmental toxicology - and access is free of charge! Visit the new DevTox Web site www.DevTox.org and let us know what you think. With the aim of further development of DevTox we would acknowledge the cooperation with further project partners.
